Prof. Dr. Mine YARIM YÜKSEL

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer's Disease

Turgutalp B., Bhattarai P., Ercetin T., Luise C., Reis R., Gurdal E. E., et al.

Journal of Medicinal Chemistry , cilt.65, sa.18, ss.12292-12318, 2022 (SCI-Expanded)

Lead Optimization and Structure-Activity Relationship Studies on Myeloid Ecotropic Viral Integration Site 1 Inhibitor

Turgutalp B., Uslu M., Helvacioglu S., Charehsaz M., Gurdal E. E., Sippl W., et al.

Journal of Medicinal Chemistry , cilt.64, sa.19, ss.14448-14464, 2021 (SCI-Expanded)

Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer's disease

Shukur K. T., Ercetin T., Luise C., Sippl W., Sirkecioğlu O., ÜLGEN M., et al.

Archiv der Pharmazie , cilt.354, sa.5, 2021 (SCI-Expanded)

Synthesis, antimicrobial, antioxidant and molecular docking studies on novel 6-methoxybenzothiazole-piperazine derivatives with propanamide chain

Alhusadi N. A., Turgutalp B., Deniz I., Acar E. T., Sipahi H., Yarim M., et al.

Current Topics in Medicinal Chemistry , cilt.20, sa.19, ss.1729-1737, 2020 (SCI-Expanded)

Synthesis and cytotoxicity studies on novel piperazinylacetamides

Bobtaina E., Gurdal E. E., Durmaz I., Atalay R. C., Yarim M.

Letters in Drug Design and Discovery , cilt.16, sa.1, ss.45-51, 2018 (SCI-Expanded)

Synthesis of novel benzothiazole-piperazine derivatives and their biological evaluation as acetylcholinesterase inhibitors and cytotoxic agents

Gurdal E. E., Turgutalp B., Gulcan H. O., Erçetin T., Sahin M. F., Durmaz I., et al.

Anti-Cancer Agents in Medicinal Chemistry , cilt.17, sa.13, ss.1837-1845, 2017 (SCI-Expanded)

Comparison of separation performance of polysaccaride-based chiral stationary phases in enantioseparation of 1-(4-chlorobenzhydryl)piperazine benzamide derivatives by HPLC

Gurdal E. E., Yarim M.

Journal of Analytical Chemistry , cilt.72, sa.2, ss.213-216, 2017 (SCI-Expanded)

Cytotoxic activities of some benzothiazole-piperazine derivatives

Gurdal E. E., Durmaz I., Cetin-Atalay R., Yarim M.

Journal of Enzyme Inhibition and Medicinal Chemistry , cilt.30, sa.4, ss.649-654, 2015 (SCI-Expanded)

Synthesis and anticancer activity evaluation of some benzothiazole-piperazine derivatives

Gurdal E. E., Buclulgan E., Durmaz I., Cetin-Atalay R., Yarim M.

Anti-Cancer Agents in Medicinal Chemistry , cilt.15, sa.3, ss.382-389, 2015 (SCI-Expanded)

Synthesis and cytotoxicity studies of novel benzhydrylpiperazine carboxamide and thioamide derivatives

Gurdal E. E., Durmaz I., Cetin-Atalay R., Yarim M.

Journal of Enzyme Inhibition and Medicinal Chemistry , cilt.29, sa.2, ss.205-214, 2014 (SCI-Expanded)

Synthesis and cytotoxic activity of novel 3-methyl-1-[(4- substitutedpiperazin-1-yl)methyl]-1H-indole derivatives

Koksal M., Yarim M., Durmaz I., Cetin-Atalay R.

Arzneimittel-Forschung/Drug Research , cilt.62, sa.8, ss.389-394, 2012 (SCI-Expanded)

Cancer cell Cytotoxicities of 1-(4-substitutedbenzoyl)-4-(4-chlorobenzhydryl)piperazine derivatives

Yarim M., Koksal M., Durmaz I., Atalay R.

International Journal of Molecular Sciences , cilt.13, sa.7, ss.8071-8085, 2012 (SCI-Expanded)

Synthesis and in vitro evaluation of novel indole-based sigma receptors ligands

Yarim M., Koksal M., Schepmann D., Wünsch B.

Chemical Biology and Drug Design , cilt.78, sa.5, ss.869-875, 2011 (SCI-Expanded)

Synthesis, enantioseparation and pharmacological activity of 4-aryl-7,7-dimethyl-5-oxo-1,2,3,4,5,6,7,8-octahydroquinazoline-2-thiones

Yarim M., Saraç S., Ertan M., Kiliç F. S., Erol K.

Arzneimittel-Forschung/Drug Research , cilt.52, sa.1, ss.27-33, 2002 (SCI-Expanded)

Separation of the enantiomers of 4-aryl-7,7-dimethyl- and 1,7,7-trimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-diones by chiral HPLC

Yarim M., SARAÇ S.

Chromatographia , cilt.56, sa.5-6, ss.307-312, 2002 (SCI-Expanded)

Synthesis and antimicrobial activity evaluation of some new adamantane derivatives

Çaliş Ü., Yarim M., Köksal M., Özalp M.

Arzneimittel-Forschung/Drug Research , cilt.52, sa.10, ss.778-781, 2002 (SCI-Expanded)

4-Aryl-6,6-dimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-diones: Synthesis, chromatographic resolution and pharmacological activity

SARAÇ S., Yarim M., Ertan M., Kiliç F., Erol K.

Pharmazie , cilt.56, sa.4, ss.298-302, 2001 (SCI-Expanded)

Crystal Structure of 1,7,7-Trimethyl-4-(4-methylphenyl)-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5- dione

Candan M. M., Kendi E., Yarim M., Saraç S., Ertan M.

Analytical Sciences , cilt.17, sa.5, ss.681-682, 2001 (SCI-Expanded)

Crystal structure of 4-(4-bromophenyl)-1,7,7-trimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5- dione

Candan M. M., Kendi E., Yarim M., Sarac S., Ertan M.

Analytical Sciences , cilt.17, sa.8, ss.1023-1024, 2001 (SCI-Expanded)

Studies on synthesis, chromatographic resolution, and antiinflammatory activities of some 2-thioxo-1,2,3,4-tetrahydropyrimidines and their condensed derivatives

Tozkoparan B., Yarim M., Saraç S., Ertan M., Kelicen P., Altinok G., et al.

Archiv der Pharmazie , cilt.333, sa.12, ss.415-420, 2000 (SCI-Expanded)

Synthesis, structural elucidation and pharmacological properties of some 5-acetyl-3,4-dihydro-6-methyl-4-(substituted phenyl)-2(1H)-pyrimidinones

Yarim M., SARAÇ S., Ertan M., Batu Ö., Erol K.

Farmaco , cilt.54, sa.6, ss.359-363, 1999 (SCI-Expanded)

Synthesis, chemical and pharmacological properties of some 4-aryl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-diones

SARAÇ S., Yarim M., Ertan M., Boydaǧ S., Erol K.

Pharmazie , cilt.53, sa.2, ss.91-94, 1998 (SCI-Expanded)

4-(2-Methylphenyl)-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-dione (I) and 4-(4-chlorophenyl)-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-dione (II)

Kendi E., SARAÇ S., Yarim M., Ertan M., Läge M., Krebs B.

Crystal Research and Technology , cilt.32, sa.6, ss.857-863, 1997 (SCI-Expanded)

Diğer Dergilerde Yayınlanan Makaleler

Primum non nocere: In silico prediction of adverse drug reactions of antidepressant drugs

Güneş S. S., Yeşil Ç., Gurdal E. E., Korkmaz E. E., Yarım M., Aydın A., et al.

Computational Toxicology , cilt.18, 2021 (Scopus)

Density functional computational and X-ray studies on pharmaceutical compound 1-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-1H-indole

ŞAHİN Z. S., YARIM YÜKSEL M., KÖKSAL AKKOÇ M.

European Journal of Chemistry , cilt.8, sa.1, ss.1-7, 2017 (Hakemli Dergi)

TOXICOLOGICAL EVALUATION OF BENZOTHIAZOLE DERIVATIVES CARRYING PIPERAZINE RING

CHAREHSAZ M., GÜRDAL HAKGÖR E. E., HELVACIOGLU S., YARIM YÜKSEL M.

MARMARA PHARMACEUTICAL JOURNAL , cilt.21, sa.2, ss.243-250, 2017 (Scopus)

Synthesis and anti-inflammatory activities of novel 5-(3,4-dichlorophenyl)- 3-[(4-substitutedpiperazin-1-yl)methyl]-1,3,4-oxadiaxole-2(3H)-thiones

Koksal M., Yarim M., Erdal A., BOZKURT A.

Drug Research , cilt.64, sa.2, ss.66-72, 2014 (Scopus)

Cytotoxic activities of some novel benzhydrylpiperazine derivatives

Gurdal E., Yarim M., Durmaz I., Cetin-Atalay R.

Drug Research , cilt.63, sa.3, ss.121-128, 2013 (Scopus)

Synthesis and in vitro calcium antagonist activity of 4-aryl-7,7-dimethyl/ 1,7,7-trimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-dione derivatives

Yarim M., Saraç S., KILIÇ F. S., Erol K.

Farmaco , cilt.58, sa.1, ss.17-24, 2003 (Scopus)

4-Aryl-5-oxo-1,2,3,4,5,6,7,8 -octahydroquinazoline-2-thione derivatives: Synthesis, enantiomeric separation and in vitro screening as calcium antagonists

SARAÇ S., Yarim M., Ertan M., Erol K., Aktan Y.

Bollettino Chimico Farmaceutico , cilt.136, sa.11, ss.657-664, 1997 (Scopus)

P110 studies on 4-aryl-2-thioxo-octahydroquinazolin-5-ones

SARAÇ S., Yarim M., Ertan M.

European Journal of Pharmaceutical Sciences , cilt.2, sa.1-2, ss.146, 1994 (Scopus)

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

Synthesis and Cytotoxicity studies on novel piperazinylacetamides

YARIM YÜKSEL M.

2nd Edition of Global Conference pn Pharmaceutics and Drug Delivery Systems, Rome-Italy, 4 - 06 Haziran 2018

Hexahydropyrimidine-2,4-diones: Synthesis and cytotoxic activity

YARIM YÜKSEL M.

19. world academy of science, engineering and technology conference, Dubai-UAE, 25 - 26 Aralık 2017

Synthesis of Novel Benzothiazole-piperazine derivatives and their biological evaluations as acetylcholinesterase inhibitors and cytotoxic agents

YARIM YÜKSEL M.

EFMC Young Medicinal Chemist Symposium, Manchester, Uk, 1 - 02 Eylül 2016

Synthesis of novel benzothiazole-piperazine derivatives and their biological evaluation as acetylcholinesterase inhibitors and cytotoxic agents

YARIM YÜKSEL M.

EFMC International Symposium on Medicinal Chemistry, Manchester, UK, 28 Ağustos - 01 Eylül 2016

Novel benzothiazole-piperazine derivatives with anticancer activity

YARIM YÜKSEL M.

Cancer 2016, Baltimore-USA, 4 - 06 Nisan 2016

Studies and Preliminary mechanistic evaluation of N-(Substituted-1,3-Benzothiazole-2-yl)-2-(4-Substituted-piperazin-1-yl) Acetamide derivatives with potent antiproliferative activity on human cancer cell lines

YARIM YÜKSEL M.

5th World Congress on Cancer Therapy, Atlanta-USA, 28 - 30 Eylül 2015

Anticancer Activity Studies on Some Benzothiazole-Piperazine Derivatives

YARIM YÜKSEL M.

World Congress on Cancer and Prevention Methods, Dubai-UAE, 27 - 29 Ağustos 2015

Synthesis And Anticancer Screening Studies of Benzothiazole-Based Piperazine Derivatives

YARIM YÜKSEL M.

4th World Congress on Cancer Science Therapy, 20 - 22 Ekim 2014

Synthesis and Anticancer Screening Studies of Indole-based piperazine Derivatives

YARIM YÜKSEL M.

3rd World Congress on Cancer Science and Therapy, 21 - 23 Ekim 2013

Synthesis and Anticancer Screening Studies of Benzhydrylpiperazine Derivatives

YARIM YÜKSEL M.

3rd World Congress on Cancer Science and Therapy, 21 - 23 Ekim 2013

Synthesis of some new 3-methyl-1-[(4-substitutedpiperazin-1-yl)methyl]-1H-indole derivatives and their cytotoxic activity

YARIM YÜKSEL M.

EFMC-ISMC 2012, 22nd International Symposium on Medicinal Chemistry, 2 - 06 Eylül 2012

Synthesis and anticancer screening studies of benzhydrylpiperazine carboxamides

YARIM YÜKSEL M.

EFMC-ISMC 2012, 22nd International Symposium on Medicinal Chemistry, 2 - 06 Eylül 2012

Studies on the synthesis of some new 3-[(4-substitutedpiperazin-1-yl)methyl]-1H-indole derivatives and their cytotoxic activity

YARIM YÜKSEL M.

ISOPS-10,10th International Symposium on Pharmaceutical Sciences, 26 - 29 Haziran 2012

Studies on the synthesis and anticancer screening of benzhydrylpiperazine derivatives

YARIM YÜKSEL M.

ISOPS-10,10th International Symposium on Pharmaceutical Sciences, 26 - 29 Haziran 2012

Synthesis and cytotoxic activity studies of sulfonylpiperazines

YARIM YÜKSEL M.

ISOPS-10,10th International Symposium on Pharmaceutical Sciences, 26 - 29 Haziran 2012

Synthesis and Antimicrobial Activity of New 5-(3,4-Dichlorophenyl)-3-{2-[4-substitutedpiperazine-1-yl]ethyl}-1,3,4-Oxadiazole-2(3H)-one Derivatives

YARIM YÜKSEL M.

IMMPC-ISPC Joint Meeting, 30 Eylül - 02 Ekim 2010

New 3,5-Disubstituted-1,3,4-Oxadiazole Derivatives with Antimicrobial Activity

YARIM YÜKSEL M.

IMMPC-ISPC Joint Meeting, 30 Eylül - 02 Ekim 2010

Antimicrobial Activity of New 3,5-Disubstituted-1,3,4-Oxadiazole-2-ones

YARIM YÜKSEL M.

InternationalPostgraduate Student Meeting on Pharmaceutical Sciences, 24 - 27 Haziran 2010

HPLC Separation of Novel 1-(4-chlorobenzhydryl)piperazine Benzamide Derivatives Using Chiral Stationary Phases

YARIM YÜKSEL M.

InternationalPostgraduate Student Meeting on Pharmaceutical Sciences, 24 - 27 Haziran 2010

Synthesis and Evaluation of Novel 5-(3,4-Dichlorophenyl)-3-Substitutedpiperazinomethyl-1,3,4-Oxadiazole-2-ones as Potential Antimicrobial Agents

YARIM YÜKSEL M.

3rd International Meeting on Pharmacy and Pharmaceutical Sciences, 9 - 12 Haziran 2010

Synthesis of N, N’-disubstituted Piperazines with Sigma Receptor Affinity

YARIM YÜKSEL M.

BioPharma World Asia 2010, 16 - 19 Mart 2010

Novel Oxadiazole Mannich Bases as Possible Microbial Agents

YARIM YÜKSEL M.

BioPharma World Asia 2010, 16 - 19 Mart 2010

Synthesis and Antimicrobial Activity of Some New 5-Aryl-3-Substitutedmethyl-1,3,4-Oxadiazole-2-thione Derivatives

YARIM YÜKSEL M.

1st Turkish-Russian Joint Meeting on Organic and Medicinal Chemistry, 14 - 17 Ekim 2009

Synthesis and Antimicrobial Studies of Novel 1-(4-Chlorobenzhydryl)piperazine Carboxamide Derivatives

YARIM YÜKSEL M.

1st Turkish-Russian Joint Meeting on Organic and Medicinal Chemistry, 14 - 17 Ekim 2009

Indole Mannich Bases as Sigma Receptor Ligands

YARIM YÜKSEL M.

ASMC Kiev09 International Synposium on Advances in Synthetic and Medicinal Chemistry, 23 - 27 Ağustos 2009

Substituted Triazolo[3,4-b]thiadiazines and Their anti-inflammatory acitivity

YARIM YÜKSEL M.

ISOPS 9th International Synposium on Pharmaceutical Sciences, 23 - 26 Haziran 2009

Design, Synthesıs and Modeling Studies of Sigma Receptors Ligands

YARIM YÜKSEL M.

XXth International Symposium on Medicinal Chemistry, 31 Ağustos - 04 Eylül 2008

QSAR Modeling on Serotonin Transporter (SERT) Ligands

YARIM YÜKSEL M.

5th International Symposium on Pharmaceutical Chemistry, 5 - 07 Eylül 2007

QSAR modeling on Sigma Receptor Ligands

YARIM YÜKSEL M.

DRD International Symposium on Drug Research Development, 17 - 20 Mayıs 2007

Antidepressant-like Effect of Some New Aryl Propane Derivative Compounds

YARIM YÜKSEL M.

DRD International Symposium on Drug Research Development, 17 - 20 Mayıs 2007

QSAR modeling of OATP-C substrates with response surface method based on a multivariate interpolation

YARIM YÜKSEL M.

15th European Symposium on Quantitative Structure-Activity Relationships Molecular Modeling (Euro QSAR 2004), İstanbul, 5 - 10 Eylül 2004

Including Tautomery in QSAR and Docking

YARIM YÜKSEL M.

15th European Symposium on Quantitative Structure-Activity Relationships Molecular Modeling (Euro QSAR 2004), 5 - 10 Eylül 2004

Response surface method based on a multivariate interpolation in QSAR modeling of organic anion transporting polypeptide Oatp1a5 substrates

YARIM YÜKSEL M.

Pharmaceutical Sciences World Congress (PSWC2004), Kyoto –Japan, 30 Haziran - 03 Temmuz 2004

Prediction and identification of new substrates for organic anion transporting polypeptide 1a5 using QSAR modeling

YARIM YÜKSEL M.

Experimental Biology 2004, 17 - 21 Nisan 2004

QSAR Modeling of Organic Anion Transporting Polypeptide 3 Substrates

YARIM YÜKSEL M.

(Pfizer) Drug Discovery 2003, AshfordSandwich, Kent-England, 24 - 26 Eylül 2003

A QSAR Study on Organic Anion Transporting Polypeptide 3 (oatp3) Substrates

YARIM YÜKSEL M.

Fourth International Symposium on Pharmaceutical Chemistry, 17 - 19 Eylül 2003

2D-QSAR Modeling of Organic Anion Transporting Polypeptide 3 Substrates

YARIM YÜKSEL M.

Pharma-Day`03, Basel-Switzerland, 11 Temmuz 2003

Synthesis and in vitro calcium antagonist activity of 4-aryl-1,7,7-trimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-diones

YARIM YÜKSEL M.

XVIIth International Symposium on Medicinal Chemistry, Barcelona, 1 - 05 Eylül 2002

A comparative molecular field analysis of organic anion transporting polypeptide 3 (Oatp3) substrates

YARIM YÜKSEL M.

EuroQSAR2002, Bournemouth, 01 Eylül 2002

Enantiomeric separation of 4-aryl-7,7-dimethyl/1,7,7-trimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-diones by chiral HPLC

YARIM YÜKSEL M.

Third International Symposium on Pharmaceutical Chemistry, Istanbul, 17 - 19 Eylül 2001

Direct enantiomeric HPLC separation of 2-thioxo-1,2,3,4-tetrahydropyrimidines and their condensed derivatives on cellulose chiral stationary phases

YARIM YÜKSEL M.

Third International Symposium on Pharmaceutical Chemistry, Istanbul, 17 - 19 Eylül 2001

4-Aryl-7,7-dimethyl-4,6,7,8-tetrahydro-(1H,3H)-quinazoline-2,5-diones: Synthesis, Enantiomeric separation and pharmacological activity

YARIM YÜKSEL M.

XVIth International Symposium on Medicinal Chemistry, Bologna-Italy, 18 - 22 Eylül 2000

Synthesis and antiinflammatory activities of some 2-thioxo-1,2,3,4-tetrahydropyrimidines and their condensed derivatives

YARIM YÜKSEL M.

” Second International Symposium on Pharmaceutical Chemistry, Ankara, 22 - 24 Eylül 1999

Synthesis, chemical and pharmacological properties of some 4-aryl-6,6-dimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-diones

YARIM YÜKSEL M.

Second International Symposium on Pharmaceutical Chemistry, Ankara, 22 - 24 Eylül 1999

Synthesis and structural elucidation of some new 2-thioxo-1,2,3,4-tetrahydropyrimidines and their condensed derivatives

YARIM YÜKSEL M.

Second International Meeting on Pharmacy Pharmaceutical Sciences, 6 - 09 Eylül 1998

Analytical resolution of 4-aryl-1,2,3,4,5,6,7,8-octahydroquinazoline-2-thiones using a cellulose chiral stationary phase

YARIM YÜKSEL M.

First International Symposium on Pharmaceutical Chemistry, Ankara, 24 - 26 Eylül 1997

Synthesis and structural elucidation of some 5-acetyl-3,4-dihydro-6-methyl-4-(substituted phenyl)-2(1H)-pyrimidinones

YARIM YÜKSEL M.

5th International Symposium on Pharmaceutical Sciences, Ankara, 24 - 27 Haziran 1997

Studies on 4-aryl-2-thioxo-octahydroquinazoline-5-ones

YARIM YÜKSEL M., SARAÇ TARHAN S., ERTAN M.

2nd European Congress of Pharmaceutical Sciences, Berlin-Germany, 04 Eylül 1994, cilt.2, ss.1-204

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