Doç. Dr. Özge ŞENSOY

Yayın Ağı

Makaleler 26

1. Computational Study of the Activation Mechanism of Wild-Type Parkin and Its Clinically Relevant Mutant.

Cinviz Z. N., Sensoy Ö.

ACS chemical neuroscience , 2025 (SCI-Expanded, Scopus)

2. Dual activity of Minnelide chemosensitize basal/triple negative breast cancer stem cells and reprograms immunosuppressive tumor microenvironment

Koksalar Alkan F., Caglayan A. B., Alkan H. K., Benson E., Gunduz Y. E., Şensoy Ö., et al.

Scientific Reports , cilt.14, sa.1, 2024 (SCI-Expanded, Scopus)

3. Improving Predictive Efficacy for Drug Resistance in Novel HIV-1 Protease Inhibitors through Transfer Learning Mechanisms

Tunc H., Yılmaz S. B., Darendeli Kiraz B. N., Sarı M., Kotil S. E., ŞENSOY Ö., et al.

Journal of Chemical Information and Modeling , cilt.64, sa.20, ss.7844-7863, 2024 (SCI-Expanded, Scopus)

4. Residues in the fructose-binding pocket are required for ketohexokinase-A activity

Ferreira J. C., Villanueva A. J., Fadl S., Al Adem K., Cinviz Z. N., Nedyalkova L., et al.

Journal of Biological Chemistry , cilt.300, sa.8, 2024 (SCI-Expanded, Scopus)

5. Synthesis, Structural Investigations, DNA/BSA Interactions, Molecular Docking Studies, and Anticancer Activity of a New 1,4-Disubstituted 1,2,3-Triazole Derivative

Göktürk T., Sakallı Çetin E., Hökelek T., PEKEL H., ŞENSOY Ö., Aksu E. N., et al.

ACS Omega , cilt.8, sa.35, ss.31839-31856, 2023 (SCI-Expanded, Scopus)

6. Nonlocal Effects of Antibiotic-Resistance-Causing Mutations Reveal an Alternative Region for Targeting on FtsW-Penicillin-Binding Protein 3 Complex of Haemophilus influenzae

Alhamwi A. B., Atilgan C., ŞENSOY Ö.

Journal of Chemical Information and Modeling , cilt.63, sa.10, ss.3094-3104, 2023 (SCI-Expanded, Scopus)

7. A New Ratio-Metric pH Probe, “ThiAKS Green” for Live-Cell pH Measurements

Akyol A., Baykal D., AKDAĞ A., ŞENSOY Ö., SON Ç. D.

Photonic Sensors , cilt.13, sa.1, 2023 (SCI-Expanded, Scopus)

8. Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS.

Ilter M., Kasmer R., Jalalypour F., Atilgan C., Topcu O., KARAKAŞ N., et al.

eLife , cilt.11, 2022 (SCI-Expanded, Scopus)

9. Mechanistic insight into impact of phosphorylation on the enzymatic steps of farnesyltransferase

PEKEL H., GÜZEL M., ŞENSOY Ö.

Protein Science , cilt.31, sa.10, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

10. Experimental and Computational Investigation of Clustering Behavior of Cyclodextrin-Perfluorocarbon Inclusion Complexes as Effective Histotripsy Agents

Kaymaz B., Mustafa W., Hall S., Vlaisavljevich E., ŞENSOY Ö., YÜKSEL DURMAZ Y.

Molecular Pharmaceutics , cilt.19, sa.8, ss.2907-2921, 2022 (SCI-Expanded, Scopus)

11. Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer

Mansoor S., Kayık G., Durdagi S., ŞENSOY Ö.

Computational and Structural Biotechnology Journal , cilt.20, ss.925-936, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

12. Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS-CoV-2 protease 3CLpro

Ferreira J. C., Fadl S., Ilter M., PEKEL H., Rezgui R., ŞENSOY Ö., et al.

FASEB Journal , cilt.35, sa.8, 2021 (SCI-Expanded, Scopus)

13. Inhibition of SARS-CoV-2 main protease: a repurposing study that targets the dimer interface of the protein

PEKEL H., Ilter M., ŞENSOY Ö.

Journal of Biomolecular Structure and Dynamics , cilt.40, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

14. Linker residues regulate the activity and stability of hexokinase 2, a promising anticancer target

Ferreira J. C., Khrbtli A., Shetler C. L., Mansoor S., Ali L., ŞENSOY Ö., et al.

Journal of Biological Chemistry , cilt.296, 2021 (SCI-Expanded, Scopus)

15. Perturb-Scan-Pull: A Novel Method Facilitating Conformational Transitions in Proteins

Jalalypour F., ŞENSOY Ö., Atilgan C., Atilgan C.

Journal of Chemical Theory and Computation , cilt.16, sa.6, ss.3842-3855, 2020 (SCI-Expanded, Scopus)

16. In silico analysis of a highly mutated gene in cancer provides insight into abnormal mrna splicing: Splicing factor 3B subunit 1k700e mutant

Samy A., Suzek B. E., ÖZDEMİR M. K., ŞENSOY Ö.

Biomolecules , cilt.10, sa.5, 2020 (SCI-Expanded, Scopus)

17. The single nucleotide β-arrestin2 variant, A248T, resembles dynamical properties of activated arrestin

ŞENSOY Ö.

Turkish Journal of Chemistry , cilt.44, sa.2, ss.409-420, 2020 (SCI-Expanded, Scopus, TRDizin)

18. Catalytically Competent Non-transforming H-RASG12P Mutant Provides Insight into Molecular Switch Function and GAP-independent GTPase Activity of RAS

Ilter M., ŞENSOY Ö.

Scientific Reports , cilt.9, sa.1, 2019 (SCI-Expanded, Scopus)

19. Utilization of biased G Protein-coupled receptor signaling towards development of safer and personalized therapeutics

Ilter M., Mansoor S., ŞENSOY Ö.

Molecules , cilt.24, sa.11, 2019 (SCI-Expanded, Scopus)

20. Prediction and targeting of interaction interfaces in G-protein coupled receptor oligomers

Schiedel A. C., Köse M., Barreto C., Bueschbell B., Morra G., ŞENSOY Ö., et al.

Current Topics in Medicinal Chemistry , cilt.18, sa.8, ss.714-746, 2018 (SCI-Expanded, Scopus)

21. Computational approaches in antibody-drug conjugate optimization for targeted cancer therapy

Melo R., Lemos A., Preto A. J., Almeida J. G., Correia J. D., ŞENSOY Ö., et al.

Current Topics in Medicinal Chemistry , cilt.18, sa.13, ss.1091-1109, 2018 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

22. Modulation of protein-protein interactions for the development of effective therapeutics - From a joint perspective of experiment and computation

Moreira I. S., ŞENSOY Ö.

Current Topics in Medicinal Chemistry , cilt.18, sa.8, ss.645-646, 2018 (SCI-Expanded, Scopus)

23. Perturbation-Response Scanning Reveals Key Residues for Allosteric Control in Hsp70

Penkler D., ŞENSOY Ö., Atilgan C., Tastan Bishop Ö.

Journal of Chemical Information and Modeling , cilt.57, sa.6, ss.1359-1374, 2017 (SCI-Expanded, Scopus)

24. FbpA iron storage and release are governed by periplasmic microenvironments

ŞENSOY Ö., Atilgan A. R., Atilgan C.

Physical Chemistry Chemical Physics , cilt.19, sa.8, ss.6064-6075, 2017 (SCI-Expanded, Scopus)

25. Understanding the Differential Selectivity of Arrestins toward the Phosphorylation State of the Receptor

ŞENSOY Ö., Moreira I. S., Morra G.

ACS Chemical Neuroscience , cilt.7, sa.9, ss.1212-1224, 2016 (SCI-Expanded, Scopus)

26. A GIPC1-palmitate switch modulates dopamine Drd3 receptor trafficking and signaling

Arango-Lievano M., ŞENSOY Ö., Borie A., Corbani M., Guillon G., Sokoloff P., et al.

Molecular and Cellular Biology , cilt.36, sa.6, ss.1019-1031, 2016 (SCI-Expanded, Scopus)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 9

1. Molecular Insight into Impact of a Mutation that Causes Variations in Clinical Outcomes of Patients with Parkinson`s Disease

Cinviz Z. N., ŞENSOY Ö.

11 th International Molecular Biology and Biotechnology Congress, Türkiye, 10 - 12 Ekim 2022, (Özet Bildiri)

2. A NOVEL APPROACH FOR ALLOSTERIC AND SPECIFIC INACTIVATION OF HEXOKINASE-2 ENZYME WHICH IS UPREGULATED IN CANCER

Mansoor S., ŞENSOY Ö.

1. International Advances in Molecular Biology Congress, İstanbul, Türkiye, 19 - 22 Eylül 2022, (Özet Bildiri) Sürdürülebilir Kalkınma

3. Understanding Impact of Membrane on Activaton of Adp-Ribosylation Factors: A New Perspective to the Activation Mechanism

Kars R. H., ŞENSOY Ö.

International Conference On Emerging Sources In Science, Türkiye, 26 - 27 Mayıs 2022, ss.233, (Özet Bildiri)

4. Manipulation of a Cryptic Site on DHFR to Combat Trimethoprim Resistance in E. coli

Çetin E., PEKEL H., ATILGAN A. R., ŞENSOY Ö., ATILGAN C.

Hunfeld 2022: “COMPUTER SIMULATION AND THEORY OF MACROMOLECULES”, Hunfeld, Almanya, 8 - 09 Nisan 2022, (Özet Bildiri)

5. In Silico Development ofPhosphorylation-Independent Arrestins Via Small Molecules

kurt m. h., morra g., ŞENSOY Ö.

6 th International BAU Drug Design Congress, İstanbul, Türkiye, 13 - 15 Aralık 2018, (Özet Bildiri)

6. Understanding Dynamics of G Protein-Coupled Receptor Oligomers for Development ofHeterobivalent Ligands:As Novel Therapeutic Candidates forTreatment ofParkinson’s Disease

Mansoor S., gülru k., DURDAĞI S., ŞENSOY Ö.

6th International BAU Drug Design Congress, İstanbul, Türkiye, 13 - 15 Aralık 2018, (Özet Bildiri)

Kitaplar 2

1. Protein Etkileşimlerinin Deneysel ve Hesaplamalı Yaklaşımlarla Bütüncül Olarak Modellenmesi

ACUNER S. E., İmat N. B., İlter M., Şamiloğlu E., KARACA EREK E., ŞENSOY Ö.

PROTEİN: Yapısı, mühendisliği, etkileşimleri, dinamiği ve ilaç tasarımındaki yeri, Dr. Öğretim Üyesi Saliha Ece ACUNER, Editör, Ankara Nobel Tıp Kitabevleri, Ankara, ss.223-237, 2021

2. G Protein-Coupled Receptors Part A

ŞENSOY Ö., almeida J. G., shabbir j., moreira i. s., morra g.

Methods in cell biology, Arun K. Shukla, Editör, Elsevier, ss.205-245, 2017