Short-Term Safety and Effectivess of Apipuncture in Knee Osteoarthritis: A Single-Arm Clinical Trial
Medical Science and Discovery, cilt.10, sa.8, ss.527-534, 2023 (Hakemli Dergi)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 10 Sayı: 8
- Basım Tarihi: 2023
- Doi Numarası: 10.36472/msd.v10i8.1007
- Dergi Adı: Medical Science and Discovery
- Derginin Tarandığı İndeksler: Index Copernicus
- Sayfa Sayıları: ss.527-534
- İstanbul Medipol Üniversitesi Adresli: Evet
Özet
Objective: Osteoarthritis, a degenerative joint disease, often poses challenges in conventional medical treatment, leading patients to explore traditional and complementary medicine options including apitherapy. Bee venom, known for its analgesic and anti-inflammatory properties, has been considered as a potential therapy. This study investigates the short-term safety and effectiveness of applying live bee venom in knee osteoarthritis patients.
Materials and Methods: Conducted at a university hospital's Apitherapy Clinic, this single-arm clinical trial enrolled individuals diagnosed with mild to moderate knee osteoarthritis (stage 2-3). A single session of live bee venom application was administered to acupuncture points ST35, EX-LE4, and ash-chi, specifically targeting the painful knee joint. Data collection involved the utilization of a Demographic Information Questionnaire and SF-12 Scale, along with a comparison of the Numerical Rating Scale (NRS), 5 Times Sit-to-Stand Test (5xSST), and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire before and after the treatment.
Results: Before the treatment, the average NRS value stood at 7.14 ± 1.7, and following the intervention, it notably decreased to 3.06 ± 2.16 (p<0.05). Additionally, the mean value for the 5xSST decreased from 14.59 ± 3.36 before treatment to 11.75 ± 2.30 after treatment. The WOMAC scale also showed a significant difference between pre- and post-treatment (p<0.05), with the mean value decreasing from 41.91 ± 18.07 before treatment to 15.57 ± 15.14 after treatment.
Conclusion: The findings of this study indicate a significant improvement in the NRS, 5xSST, and WOMAC scales after the administration of live bee venom for knee osteoarthritis patients.