Cytotoxic activity of the root and fruit extracts of Heptaptera anisoptera (DC.) Tutin

Creative Commons License

TOSUN F., MİSKİ M.

Acta Pharmaceutica Sciencia, cilt.58, sa.1, ss.21-25, 2020 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 58 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.23893/1307-2080.aps.05801
  • Dergi Adı: Acta Pharmaceutica Sciencia
  • Derginin Tarandığı İndeksler: Scopus, EMBASE
  • Sayfa Sayıları: ss.21-25
  • Anahtar Kelimeler: Apiaceae, Cytotoxic activity, Heptaptera anisoptera
  • İstanbul Medipol Üniversitesi Adresli: Evet

Özet

Cytotoxic activities of the root and fruit extracts of Heptaptera anisoptera (DC.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the roots of H. anisoptera showed cytotoxic activity with IC50 values of 3.1 and 3.9 ug/mL on the COLO205 and KM12 cell lines, respectively. Cytotoxic activity of the dichloromethane extract of the fruits were similar to those of root extract with IC50 values of 5.5 and 4.8 ug/mL on the COLO205 and KM12 cell lines, respectively.