Research Information System
Turk Noroloji Dergisi, vol.18, no.4, pp.151-154, 2012 (Scopus)
Objective: Parkinson's disease (PD) is characterized by motor dysfunction, and is also a non-motor disorder. Olfactory dysfunction (OD) is a non-motor symptom in PD. In this study, we aimed to investigate whether OD varies among subtypes of PD. Ma te ri al and Met hod: Patients comprised 28 patients with idiopathic PD (23 male and 5 female) with a mean age of 64.96 ± 7.49 years. The patients were divided into tremor-dominant type (TDT), akinetic-rigid type (ART) and mixed type (MT) by means of part III of Unified Parkinson's Disease Rating Scale. Patients were asked whether they had a relative with tremor or PD. University of Pennsylvania Smell Identification Test-40 (UPSIT-40) was used to test olfactory function. Patients with any factor that may influence olfactory function were excluded. Re sults: Fourteen patients were classified as TDT, 12 as ART, and 2 as MT. There were no significant differences in mean age, UPDRS part III, and UPDRS total scores. The UPSIT scores were the highest in the MT group and lowest in the ART group, but there was no statistically significant difference. Dis cus si on: Our results do not prove a difference in OD between subtypes of PD, but suggest that ART patients might have a poor ability to identify odors. (Turkish Journal of Neurology 2012; 18:151-54).