Pacemaker implantation in patients with tricuspid prosthesis is a challenging situation. It is not possible to pass the pacing lead through tricuspid valve in these patients. Therefore, ventricular pacing can be achieved either epicardial or endocardial left ventricular stimulation. For epicardial pacing, lead implantation can be done transvenously via coronary sinus or surgically. In this paper, we present a patient who had complete atrioventricular block (CAVB) following tricuspid valve prosthesis implantation and treated with epicardial pacing via coronary sinus. In patients who develop CAVB after tricuspid valve replacement, can be treated with permanent pacemaker implantation via CS. This technique enables a minimally invasive approach and effective stimulus in patients with inaccessible right ventricle because of the presence of prosthetic tricuspid valve.