Hyperimmunoglobulin E syndrome (Job's syndrome) in a-22-month old girl and IVIG treatment

Aka S., Sami Yazar A., CERAN Ö.

Marmara Medical Journal, vol.16, no.3, pp.207-210, 2003 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 3
  • Publication Date: 2003
  • Journal Name: Marmara Medical Journal
  • Journal Indexes: Scopus
  • Page Numbers: pp.207-210
  • Keywords: Hyperimmunoglobulin E syndrome, Job's syndrome
  • Istanbul Medipol University Affiliated: Yes


Hyperimmunoglobulin E syndrome is a rare disorder characterized by pruritic dermatitis, recurrent staphylococcal skin abscesses and extremely elevated concentrations of immunoglobulin E in serum. We report a patient who has pruritic vesiculopapules, recurrent episodes of skin abscesses on the scalp and face, and respiratory problems from the age of ten days (severe cough, wheezing, acute otitis media, pneumonia). She was diagnosed as Hyper-IgE syndrome and treated with IVIG along with antibiotics.