An investigation about the genotoxic activities of some herbal teas used as folk medicine

Alpertunga B., OMURTAG G. Z., Ozmentese N.

Acta Pharmaceutica Turcica, vol.39, no.3, pp.105-110, 1997 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 3
  • Publication Date: 1997
  • Journal Name: Acta Pharmaceutica Turcica
  • Journal Indexes: Scopus
  • Page Numbers: pp.105-110
  • Keywords: Genotoxicity, Herbal teas, Umu test
  • Istanbul Medipol University Affiliated: No

Abstract

In this research the genotoxic activities of some herbal teas used as folk medicine were investigated by the umu-test using a tester strain Salmonella typhimurium TA 1535/pSK 1002 carrying the umuC-lacZ fused gene with (+S9) and without (-S9) metabolic activation. The induction of umu gene expression was monitored by measuring the cellular β-galactosidase activity produced by fusion gene using a colorimetric method. Consequently, from 10 herbal teas used in this research, only two of them showed weak genotoxicity.