An investigation about the genotoxic activities of some herbal teas used as folk medicine


Alpertunga B., OMURTAG G. Z., Ozmentese N.

Acta Pharmaceutica Turcica, cilt.39, sa.3, ss.105-110, 1997 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 3
  • Basım Tarihi: 1997
  • Dergi Adı: Acta Pharmaceutica Turcica
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.105-110
  • Anahtar Kelimeler: Genotoxicity, Herbal teas, Umu test
  • İstanbul Medipol Üniversitesi Adresli: Hayır

Özet

In this research the genotoxic activities of some herbal teas used as folk medicine were investigated by the umu-test using a tester strain Salmonella typhimurium TA 1535/pSK 1002 carrying the umuC-lacZ fused gene with (+S9) and without (-S9) metabolic activation. The induction of umu gene expression was monitored by measuring the cellular β-galactosidase activity produced by fusion gene using a colorimetric method. Consequently, from 10 herbal teas used in this research, only two of them showed weak genotoxicity.