Prediction of infarct size using two-dimensional speckle tracking echocardiography in acute myocardial infarction

Doğan C., Bayram Z., Candan Ö., Omaygenç O., Yılmaz F., Acar R. D., ...More

Echocardiography, vol.34, no.3, pp.376-382, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.1111/echo.13457
  • Journal Name: Echocardiography
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.376-382
  • Keywords: myocardial infarction, myocardial perfusion, radionuclide imaging, strain
  • Istanbul Medipol University Affiliated: Yes


Background: This study aimed to determine the myocardial damage (infarct size provided by cardiac single-photon emission tomography) in early stages of the infarction using longitudinal strain and rotational parameters of the left ventricle. Methods: The study included 66 patients with anterior myocardial infarction (AMI) and 62 patients with inferior myocardial infarction (IMI) who underwent primary percutaneous intervention as well as a control group consisting of 50 healthy subjects. LV rotational parameters based on parasternal short-axis views in basal and apical planes and global longitudinal strain were measured with apical four-chamber, apical two-chamber, and apical long-axis views. Results: There was a significant positive correlation between infarct size and GLPSavg (r=−.55 <.001), GTOR angle (r=−.52, P<.001), apical rotation angle (r=−.40 <.001, and EF (r=−.43, <.001). While cutoff values were GLPSavg: 11.9 (AUC=0.78), GTOR angle: 11.4° (AUC=0.77), apical rotation angle: 7.1° (AUC=0.76) for patients with an infarct size greater than 20%, the cutoff values were GLPSavg: 10.7 (AUC=0.75), GTOR angle: 8.7° (AUC=0.86), apical rotation angle: 4.35° (AUC=0.87) for those with an infarct size greater than 40%. Conclusion: GLPSavg, GTOR angle, and apical rotation angle values may be used to determine the extent of infarction in early post-MI period, thereby allowing precautions to be taken for remodeling in early stages.