Effect of intraovarian platelet rich plasma injection during hysterectomy on ovarian reserve and sexual life
Ginekologia Polska, cilt.97, sa.2, ss.102-109, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 97 Sayı: 2
- Basım Tarihi: 2026
- Doi Numarası: 10.5603/gpl.105291
- Dergi Adı: Ginekologia Polska
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Central & Eastern European Academic Source (CEEAS), Directory of Open Access Journals
- Sayfa Sayıları: ss.102-109
- Anahtar Kelimeler: AMH, fertility, FSFI, menopause, PRP
- İstanbul Medipol Üniversitesi Adresli: Evet
Özet
Objectives: Low ovarian reserve is a major concern as older women seek pregnancy. Women 35 and older who want to conceive have fewer high-quality oocytes, which is linked to a drop in Anti-Müllerian hormone (AMH). Women in this age bracket may need hysterectomy for abnormal uterine bleeding, leiomyomas, and pre-/malignant reasons. Those with preserved ovaries after hysterectomy nevertheless experience menopause. This circumstance impacts women’s sexuality. Interventions to improve ovarian function in this age group may illuminate both concerns. Material and methods: We did an observational case-control study of 35–50-year-old individuals who had hysterectomy for a benign disease. The trial group received perioperative PRP for their ovaries, while the control group received no treatment. Patients’ preoperative AMH and Female Sexual Function Index (FSFI) scores were compared to those 3 months following surgery. Results: Our study found a substantial drop in postoperative AMH levels in the control group (p < 0.001), whereas the PRP group showed a slight increase in AMH levels. The PRP group has a significant difference in preoperative and post-operative AMH levels (p = 0.0001). The PRP group had a much higher total FSFI score. Subgroup analysis shows this variation in lubrication, orgasm, contentment, and pain. The PRP group had substantial differences in orgasm, pleasure, and pain pre-and post-operation. Conclusions: PRP supports ovarian regeneration but has limited benefits. This information should be used to build standardized PRP protocols and undertake more extensive investigations by applying PRP to numerous organs, including the ovaries.