Aspergillus fumigatus infection as a delayed manifestation of prosthetic knee arthroplasty and a review of the literature

YILMAZ M., METE B., Özaras R., KAYNAK G., Tabak F., Tenekecioǧlu Y., ...More

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, vol.43, no.8, pp.573-578, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 43 Issue: 8
  • Publication Date: 2011
  • Doi Number: 10.3109/00365548.2011.574294
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.573-578
  • Keywords: Aspergillus fumigatus, prosthetic infection, total knee arthroplasty, amphotericin B
  • Istanbul Medipol University Affiliated: Yes


Fungal infection after total joint arthroplasty is a very rare but serious complication and a challenge to the treating and consulting physicians. The literature includes little information about the treatment protocol for Aspergillus infection after total knee arthroplasty, since only 3 cases have been reported. We describe the case of a non-immunocompromised patient who lacked predisposing risk factors and presented with pain and swelling. An aspiration under sterile conditions revealed Aspergillus fumigatus. The patient was treated successfully with a 2-stage exchange reimplantation and 6-week course of liposomal amphotericin B. At 4 y after reimplantation, the patient had no evidence of infection or pain. © 2011 Informa Healthcare.