Effects of electromagnetic radiation on neurogenesis and gene expression in amniocytes

Uzun C., Erdal N., İzci Ay Ö., Karakaş Ü., Derici Yildırım D., Durukan H., ...More

Toxicological and Environmental Chemistry, vol.105, no.8-10, pp.281-301, 2023 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 105 Issue: 8-10
  • Publication Date: 2023
  • Doi Number: 10.1080/02772248.2024.2304014
  • Journal Name: Toxicological and Environmental Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Agricultural & Environmental Science Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Communication Abstracts, Compendex, Environment Index, Food Science & Technology Abstracts, Geobase, Greenfile, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Page Numbers: pp.281-301
  • Keywords: amniotic fluid cells, Electromagnetic radiation, gene expression, neurogenesis, Wnt pathway
  • Istanbul Medipol University Affiliated: Yes

Abstract

The aim of the study was to investigate the genetic effects of commonly used radiofrequency on the amniocytes of pregnant women by examining the changes in the expression of genes related to signal transduction and neurogenesis induced by electromagnetic fields of radiofrequencies of 1800 and 2100 MHz by real-time PCR. Upon exposure of the amniocytes to electromagnetic radiation of 2100 MHz at high field strength, the expression levels of genes with important functions in the Wnt signaling pathways as well as neurogenesis-related genes were increased. The findings suggest that radiofrequency at high field strengths can have genotoxic effects during pregnancy.