Prenatal diagnosis of congenital hallux varus deformity associated with pericentric inversion of chromosome 9


Gürel S. A.

Journal of Obstetrics and Gynaecology Research, cilt.41, sa.4, ss.628-630, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/jog.12603
  • Dergi Adı: Journal of Obstetrics and Gynaecology Research
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.628-630
  • Anahtar Kelimeler: chromosome 9 inversion, congenital hallux varus, prenatal diagnosis, ultrasonography
  • İstanbul Medipol Üniversitesi Adresli: Hayır

Özet

Congenital hallux varus is a rare deformity of the great toe characterized by adduction of the hallux and medial displacement of the first metatarsophalangeal joint. Prenatal diagnosis of congenital hallux varus is presented herein. A 32-year-old woman was referred to our unit due to significant deviation of the fetal right great toe at 22+2 weeks of pregnancy. Ultrasound examination revealed a thick and short great toe, which was significantly angulated medially on the right side. Amniocentesis was performed and the result was reported as inv(9) (p11;q12). After delivery, the clinical examination confirmed the prenatal diagnosis. To our knowledge, this is the first reported prenatal diagnosis of an isolated congenital hallux varus. Congenital hallux varus can be diagnosed easily in the prenatal period by 2-D and 4-D ultrasonography. Prenatal karyotyping should be taken into consideration, especially in the presence of associated anomalies, such as polydactyly and clubfoot.