Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS

TOSUN F., TAMER U.

Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.33, sa.1, ss.7-9, 2004 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 1
  • Basım Tarihi: 2004
  • Dergi Adı: Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.7-9
  • Anahtar Kelimeler: Heliotropium europaeum, Pyrrolizidine alkaloids
  • İstanbul Medipol Üniversitesi Adresli: Hayır

Özet

In the current research, alkaloid extract obtained from the seeds of Heliotropium europaeum L. collected from ]Köprübaşi (Diyarbakir Turkey) was analysed by using GC-MS method. The total pyrrolizidine alkaloid and tertiary base content of the seeds of Heliotropium europaeum were found to be 0.28% and 0.02% respectively. Higher percentage of alkaloids were present as N-oxides (92.86% of the alkaloids). Alkaloids found in the tertiary base fraction and total alkaloid fraction were identified as europine, heliotrine, supinine, heleurine, lasiocarpine and 7-angelylheliotrine.