Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS


Ankara Universitesi Eczacilik Fakultesi Dergisi, vol.33, no.1, pp.7-9, 2004 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 1
  • Publication Date: 2004
  • Journal Name: Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.7-9
  • Keywords: Heliotropium europaeum, Pyrrolizidine alkaloids
  • Istanbul Medipol University Affiliated: No


In the current research, alkaloid extract obtained from the seeds of Heliotropium europaeum L. collected from ]Köprübaşi (Diyarbakir Turkey) was analysed by using GC-MS method. The total pyrrolizidine alkaloid and tertiary base content of the seeds of Heliotropium europaeum were found to be 0.28% and 0.02% respectively. Higher percentage of alkaloids were present as N-oxides (92.86% of the alkaloids). Alkaloids found in the tertiary base fraction and total alkaloid fraction were identified as europine, heliotrine, supinine, heleurine, lasiocarpine and 7-angelylheliotrine.