Are Haller Cells and Concha Bullosa Risk Factors for the Development of Chronic Sinusitis? A 3D-CT Volumetric Study
17th International Symposium of Clinical and Applied Anatomy, Vienna, Avusturya, 3 - 06 Eylül 2026, cilt.267, sa.152887, ss.75, (Özet Bildiri)
- Yayın Türü: Bildiri / Özet Bildiri
- Cilt numarası: 267
- Basıldığı Şehir: Vienna
- Basıldığı Ülke: Avusturya
- Sayfa Sayıları: ss.75
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- İstanbul Medipol Üniversitesi Adresli: Evet
Özet
Objective: This study aimed to evaluate the effects of Haller cells and concha bullosa on maxillary sinus and ethmoidal infundibulum volumes in patients with chronic maxillary sinusitis and to investigate their association with the disease.
Methods: Paranasal sinus CT images of 100 patients with bilateral chronic maxillary sinusitis from Istanbul Medipol University Hospitals were retrospectively analyzed. A total of 200 measurements were performed on the right and left osteomeatal complexes using 3DSlicer. Cases were divided into four groups: control without Haller cells or concha bullosa (n=70), concha bullosa-only (n=56), Haller cell-only (n=32), and “sandwich” group with coexistence of Haller cells and concha bullosa (n=42).
Results: No statistically significant difference was found between the groups with Haller cells and the control group for concha bullosa prevalence (p=0.619). Maxillary sinus volume was significantly higher in the groups with Haller cells than in the control group (p<0.001). Ethmoidal infundibulum volume did not differ significantly among the groups (p=0.219).
Conclusion: The significant association between increased maxillary sinus volume and Haller cell presence suggests that maxillary and ethmoid sinus expansion may occur independently during the same period due to unknown genetic and environmental factors. Although ethmoidal infundibulum volume did not differ significantly, we believe this passage may adapt its geometry in response to sinonasal variations and, consequently, disrupt the maxillary sinus ventilation pattern, slow mucociliary flow, and lead to functional obstruction. Overall, Haller cells, alone or together with concha bullosa, were associated with anatomical changes in osteomeatal complex in patients with chronic maxillary sinusitis.
Funding sources: No financial support was received for this study.
Disclosure statement: The authors have no conflict of interest to declare.
Objective: This study aimed to evaluate the effects of Haller cells and concha bullosa on maxillary sinus and ethmoidal infundibulum volumes in patients with chronic maxillary sinusitis and to investigate their association with the disease.
Methods: Paranasal sinus CT images of 100 patients with bilateral chronic maxillary sinusitis from Istanbul Medipol University Hospitals were retrospectively analyzed. A total of 200 measurements were performed on the right and left osteomeatal complexes using 3DSlicer. Cases were divided into four groups: control without Haller cells or concha bullosa (n=70), concha bullosa-only (n=56), Haller cell-only (n=32), and “sandwich” group with coexistence of Haller cells and concha bullosa (n=42).
Results: No statistically significant difference was found between the groups with Haller cells and the control group for concha bullosa prevalence (p=0.619). Maxillary sinus volume was significantly higher in the groups with Haller cells than in the control group (p<0.001). Ethmoidal infundibulum volume did not differ significantly among the groups (p=0.219).
Conclusion: The significant association between increased maxillary sinus volume and Haller cell presence suggests that maxillary and ethmoid sinus expansion may occur independently during the same period due to unknown genetic and environmental factors. Although ethmoidal infundibulum volume did not differ significantly, we believe this passage may adapt its geometry in response to sinonasal variations and, consequently, disrupt the maxillary sinus ventilation pattern, slow mucociliary flow, and lead to functional obstruction. Overall, Haller cells, alone or together with concha bullosa, were associated with anatomical changes in osteomeatal complex in patients with chronic maxillary sinusitis.
Funding sources: No financial support was received for this study.
Disclosure statement: The authors have no conflict of interest to declare.