Comparative evaluation of postoperative pain intensity after single-visit and multiple-visit retreatment cases: A prospective randomized clinical trial Avaliação comparativa da intensidade da dor pos-operatoria após casos de retratamento em sessao unica ou multipla: Estudo clínico randomizado prospectivo

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UYAN H. M., OLCAY K., Özcan M.

Brazilian Dental Science, vol.21, no.1, pp.26-36, 2018 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.14295/bds.2018.v21i1.1515
  • Journal Name: Brazilian Dental Science
  • Journal Indexes: Scopus
  • Page Numbers: pp.26-36
  • Keywords: Intracanal medicaments, Multiple-visit, Postoperative pain, Retreatment, Single-visit
  • Istanbul Medipol University Affiliated: Yes


Objectives: This study was designed to evaluate postoperative pain after endodontic retreatment. Material and Methods: Asymptomatic, multirooted molar & premolar teeth requiring retreatment with 2–5 mm periapical lesions were included Seventy-eight teeth were randomly placed in four groups (n=20): single-visit (control, group 1), Ledermix (group 2), metronidazole, ciprofloxacin, minocycline mixture (group 3), calcium hydroxide (group 4). The postoperative pain was recorded using a VAS at 6, 12, 24, and 48 h after retreatment. Statistical evaluation was performed using Two-Way Repeated Measures ANOVA and Tukey test. Results: Mild pain occurred in 67.5%, moderate in 30%, and flare-ups in 2.5%, and there was a significant difference between the groups (p<0.01). Significantly lower postoperative pain was observed in TAP and CaOH2 groups (p<0.05). In the 6, 12, and 24 h intervals, there was a significant difference in the pain levels (p<0.05). Conclusion: TAP and CaOH2 are effective for reducing postoperative pain after retreatment.