Interplay of vitamin D, vitamin B 12 , homocysteine and bone mineral density in postmenopausal females


Tariq S., Tariq S., Lone K. P.

Health Care for Women International, vol.39, no.12, pp.1340-1349, 2018 (SSCI) identifier identifier

Abstract

Osteoporosis is most common age related, multifactorial disease. The aim of the researchers were to discover the association between serum homocysteine, vitamin D, vitamin B 12 and bone mineral density in postmenopausal non-osteoporotic and osteoporotic females. In this cross- sectional study, 156 postmenopausal females between 50–70 years of age were recruited and divided into two groups, non-osteoporotic (n = 52) and osteoporotic (n = 104). There was significant negative correlation of homocysteine with vitamin D and B 12 in postmenopausal non-osteoporotic and homocysteine with vitamin B 12 in postmenopausal osteoporotic females. Serum homocysteine levels were predicted by vitamin D in postmenopausal non-osteoporotic and vitamin B 12 in postmenopausal osteoporotic females.