Outcomes of the novolimus-eluting bioresorbable vascular scaffold in real world clinical practice
Minerva Cardiology and Angiology, cilt.69, sa.3, ss.261-268, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 69 Sayı: 3
- Basım Tarihi: 2021
- Doi Numarası: 10.23736/s2724-5683.20.05138-5
- Dergi Adı: Minerva Cardiology and Angiology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.261-268
- Anahtar Kelimeler: Percutaneous coronary intervention, Cardiovascular system, Novolimus
- İstanbul Medipol Üniversitesi Adresli: Evet
Özet
BaCKgroUNd: Most of the current data regarding the use of bioresorbable scaffolds (BrS) come from everolimus-eluting stent platforms. adverse events with the everolimus-eluting BrSs which are the most comprehensively characterized BRS, hampered the clinical use of other BRS. There is paucity of published data regarding long term use of novolimus-eluting BrS. METHODS: This study sought to evaluate the performance of novolimus-eluting BRS device at midterm follow-up in real world clinical practice. one hundred and forty-four patients (mean age 57.5±9.7 years, 78.5% male) treated with 206 scaffolds between october 2015 and december 2017 were enrolled. a device-oriented composite endpoint (doCe) comprising cardiac death, target vessel myocardial infarction (TV-MI), clinically driven target lesion revascularization (TLR) and rate of scaffold thrombosis were investigated. RESULTS: During a mean follow-up of 33±9 months, DOCE occurred in 9 patients (6.3%) of which cardiac death occurred in 2 patients (1.4%), and clinically driven TLR in 7 patients (4.9%), TV-MI in one patient. Target vessel revascularization (TVR) was observed in nine patients. None of the patients experienced scaffold thrombosis. CONCLUSIONS: The use of novolimus-eluting BRS in this real-world population achieved good clinical outcomes.