The effect of vaginal cleansing performed with normal saline solution or povidone-iodine before elective caesarean section on postoperative maternal morbidity and infection: A prospective randomized controlled study


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KANZA GÜL D.

Marmara Medical Journal, vol.34, no.1, pp.33-39, 2021 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.5472/marumj.866504
  • Journal Name: Marmara Medical Journal
  • Journal Indexes: Scopus, Academic Search Premier, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.33-39
  • Keywords: Caesarean section, Maternal morbidity, Postoperative infection, Vaginal cleansing, Saline solution, Povidone-iodine
  • Istanbul Medipol University Affiliated: Yes

Abstract

Objective: The present study was designed to determine the effect of vaginal cleansing performed with saline solution or povidone-iodine before elective cesarean section on postpartum maternal morbidity and postoperative infection. Patients and Methods: One hundred and eighty primiparae, awaiting elective caesarean section, were assigned into the following three groups, Group1 (saline solution vaginal cleansing for 30s, n:60); Group2 (povidone-iodine vaginal cleansing for 30s, n:60); Group3 (control group, n:60). Results: There were statistically significant differences between the 3 groups in terms of the median values for the postoperative C-reactive protein (CRP) and fever, and visual analogue scale (VAS) score (p<0.001). The median value for the postoperative CRP level was 26.5 mg/dl, 59.5mg/dl and 62.3mg/dl in the saline solution, povidone-iodine and control groups respectively. The median value for the VAS score was 3,4 and 4; the incidence of the patients with fever >38°C was 1.7%, 3.4% and 10% in the saline solution, povidone-iodine and control groups, respectively. Conclusion: Vaginal cleansing with normal saline solution or povidone-iodine before caesarean section significantly reduced postoperative pain, fever, and CRP levels. Cleansing of the vagina before cesarean section clinically reduced the number of postcaesarean wound site infections, and endometritis; however, the reduction was not statistically significant.