Akademik Veri Yönetim Sistemi
ACTA Pharmaceutica Sciencia, cilt.63, sa.3, 2025 (Hakemli Dergi)
ABSTRACT Patients with Gram-negative bacilli bloodstream infections (GNB-BSIs) have a high mortality and morbidity rate. This can result in an increased length of hospitalizations and risk of polypharmacy. This study investigates drug-related problems (DRPs) and associated factors during antimicrobial treatment in GNB-BSI patients. The prospective observational study was conducted between April 2023 and April 2024 at a 970-bed tertiary care university hospital in Istanbul. The study included 150 adult patients with a mean age of 58 years, and 57.3% of patients were male. Multivariable logistic regression analysis highlighted significant associations between DRPs and the presence of comorbidities, the duration of the patient’s hospitalization, time to adequate antimicrobial therapy and the number of prescribed medications per patient (p<0.05). In conclusion, this study underscores the significance of clinical pharmacists’ collaboration with clinicians in the identification and assessment of drug-related problems (DRPs) within the clinical department.