Effect of BCG vaccine on tuberculin skin tests in 7-11-year-old children

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Bozaykut A., Atay E., Sevim H., Atay Z., Ceran Ö.

Acta Paediatrica, International Journal of Paediatrics, vol.93, no.8, pp.1033-1035, 2004 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 93 Issue: 8
• Publication Date: 2004
• Doi Number: 10.1080/08035250410024970
• Journal Name: Acta Paediatrica, International Journal of Paediatrics
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1033-1035
• Keywords: BCG, children, tuberculin skin test
• Istanbul Medipol University Affiliated: Yes

Abstract

Aim: To determine the effect of Bacillus Calmette Guerin (BCG) vaccination on tuberculin skin test responses in 7-11-year-old children, and also to clarify whether the number of vaccinations and the time interval between vaccination and tuberculin skin test have an effect on the test responses. Method: 1200 primary school children were evaluated for the presence and number of BCG scars. They were then given 5 TU PPD-S intra-dermally. Seventy-two hours after the application of tests, PPD indurations were measured. Results: Mean indurations were 3.7 ± 3.9, 6.5 ± 5.4 and 9.2 ± 7.1 mm in children with no scar, one scar and two scars, respectively. No statistical difference was found between mean induration of children with one scar and those with two scars. Conclusion: The effect of the number of BCG vaccinations and the time interval between vaccination and tuberculin skin test application on tuberculin skin test responses was statistically insignificant.