Evaluation of sialic acid levels in patients with hydatidiform mole: A preliminary study

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Özcan H., Öztürk E., Sucu S., Uǧur M., Kutlar I., Balat Ö., ...More

Clinical and Experimental Obstetrics and Gynecology, vol.43, no.3, pp.414-416, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.12891/ceog2156.2016
  • Journal Name: Clinical and Experimental Obstetrics and Gynecology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.414-416
  • Keywords: Hydatidiform mole, Sialic acid, Pregnancy
  • Istanbul Medipol University Affiliated: Yes


Purpose of investigation: This study aims to investigate whether hydatidiform mole (HM) disease with malignant potential is significantly associated with increased sialic acid (SA) levels. Materials and Methods: A total of 114 women were enrolled in this study. Patients were divided into three groups including HM (Group 1, n=34), control group including non-pregnant healthy patients (Group 2, n=42), and another control group including healthy pregnant patients within 12 weeks of gestation (Group 3, n=38). Serum-free SA levels were measured. Results: There was a statistically significant difference in serum-free SA levels among the groups (p ≤ 0.001). Patients with HM had significantly higher levels compared to the control groups. Conclusion: The present study results showed that there was a significant correlation between HM and serum SA level.