Akademik Veri Yönetim Sistemi
Annals of Medical Research, cilt.28, sa.3, ss.516-519, 2021 (Hakemli Dergi)
Aim: Studies on the antimicrobial effectiveness of saponins against oral pathogens are conflicting. Therefore, this study aimed toevaluate the antimicrobial activity of saponins from three different extracts of Sapindus mukorossi and Saponaria officinalis plantsagainst Streptococcus mutans and Enterococcus faecalis.Materials and Methods: The fruit of Sapindus mukorossi and the root of Saponaria officinalis materials were sliced into small piecesand macerated with hexane, ethyl acetate (EtOAc) and methanol (MeOH), in this order. The antimicrobial activity of the extractsagainst Streptococcus mutans and Enterococcus faecalis was determined by the broth microdilution method based on the minimuminhibitory concentrations (MIC) of each extract. Results: Except for the hexane extract of Saponaria Officinalis, all extracts of both plants had an inhibitory activity against thetested microorganisms. Higher MIC values were obtained against Enterococcus faecalis than Streptococcus Mutans. The lowestMIC values for both Sapindus mukorossi and Saponaria officinalis were against Streptococcus mutans (4 mg/ml).Conclusion: Saponins extracted from Sapindus mukorossi and Saponaria officinalis have a potential antibacterial activity againstoral pathogens. They may be used as an ingredient in dental agents.