Performance comparison of Next Generation sequencing platforms

Ergüner B., Üstek D., Saʇiroʇlu M. Ş.

37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 25 - 29 August 2015, vol.2015-November, pp.6453-6456 identifier identifier identifier

  • Publication Type: Conference Paper / Full Text
  • Volume: 2015-November
  • Doi Number: 10.1109/embc.2015.7319870
  • City: Milan
  • Country: Italy
  • Page Numbers: pp.6453-6456
  • Istanbul Medipol University Affiliated: Yes


Next Generation DNA Sequencing technologies offer ultra high sequencing throughput for very low prices. The increase in throughput and diminished costs open up new research areas. Moreover, number of clinicians utilizing DNA sequencing keeps growing. One of the main concern for researchers and clinicians who are adopting these platforms is their sequencing accuracy. We compared three of the most commonly used Next Generation Sequencing platforms; Ion Torrent from Life Technologies, GS FLX+ from Roche and HiSeq 2000 from Illumina.