Performance comparison of Next Generation sequencing platforms

Ergüner B., Üstek D., Saʇiroʇlu M. Ş.

37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, İtalya, 25 - 29 Ağustos 2015, cilt.2015-November, ss.6453-6456 identifier identifier identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası: 2015-November
  • Doi Numarası: 10.1109/embc.2015.7319870
  • Basıldığı Şehir: Milan
  • Basıldığı Ülke: İtalya
  • Sayfa Sayıları: ss.6453-6456
  • İstanbul Medipol Üniversitesi Adresli: Evet

Özet

Next Generation DNA Sequencing technologies offer ultra high sequencing throughput for very low prices. The increase in throughput and diminished costs open up new research areas. Moreover, number of clinicians utilizing DNA sequencing keeps growing. One of the main concern for researchers and clinicians who are adopting these platforms is their sequencing accuracy. We compared three of the most commonly used Next Generation Sequencing platforms; Ion Torrent from Life Technologies, GS FLX+ from Roche and HiSeq 2000 from Illumina.