Retina-Vitreus, vol.22, no.4, pp.289-292, 2014 (Scopus)
Purpose: Aim: To evaluate efficacy and safety of pars plana vitrectomy (PPV) in non-tractional diabetic macular edema (DME). Materials and Methods: Eighteen eyes of 18 patients which underwent PPV by virtue of resistance to combined intravitreal triamcionolon acetonide injection and macular laser photocoagulation were rewieved retrospectively. Results: Baseline mean best spectacle corrected visual acuity (BSCVA) improved from 0.83±0.29 logMar to 0.70±0.31 log- Mar at the last follow-up visit after surgery (p=0.0686). Baseline mean macular thickness measured by OCT reduced from 434±72 μ (312-554 μ) to 369±51 μ (277-468 μ) at the last follow-up visit postoperatively (p<0.0001). Conclusion: PPV is controversial in the treatment of diffuse DME. It can be used as an adjunctive treatment in case of resistance to macular laser photocoagulation and intravitreal anti-VEGF injection which are less invasive methods.