The role of platelets as an early prognostic factor in preterm labor Preterm eylemde erken prognostik faktör olarak trombositlerin rolü

Aktün L. H.

Medeniyet Medical Journal, vol.32, no.2, pp.101-105, 2017 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.5222/mmj.2017.101
  • Journal Name: Medeniyet Medical Journal
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.101-105
  • Keywords: Mean platelet volume, Platelet, Preterm labor
  • Istanbul Medipol University Affiliated: Yes


The aim of this study was to evaluate changes in platelet index in preterm labor and to investigate whether it has a predictive value for the diagnosis of preterm labor. Retrospectively, women with 140 preterm labor and 130 healthy pregnant women who were examined between 2013 and 2016 were included in the study. Demographic, obstetric and laboratory results (hemoglo-bin, hematocrit, white blood cell, platelet, platelet distribution width, mean platelet volume) of 270 pregnants were compared. Mean platelet volume (MPV) and hemoglobin levels were significantly lower in the preterm labor group (p<0.001, p=0.01, res-pectively). Platelet distribution width (PDW) levels were higher in the preterm labor group (p=0.05). There was no significant difference between platelet counts in both groups. Successful balance between coagulation and anticoagulation is very important for the induction and progression of the pregnancy. For this, many markers such as PDW, MPV have been studied. More recently, however, blood subtypes are thought to be able to provide clues for prognosis and diagnosis in chronic low-grade inflammatory diseases. MPV levels in preterm labor suggest that high levels of low PDW levels may be due to pathologic thrombocytic activation and inflammation. Further PDW levels may alert the obstetrician to the risk of preterm labor. However, there is a need for further study for the beneficial role of platelets in the diagnosis of preterm labor.