Effect of three different remineralizing agents on artificial erosive lesions of primary teeth


ÜSTÜN N., GÜVEN Y.

Australian Dental Journal, cilt.67, sa.3, ss.271-280, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1111/adj.12922
  • Dergi Adı: Australian Dental Journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, CINAHL, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.271-280
  • Anahtar Kelimeler: Erosive lesion, in vitro, primary teeth, self-assembling peptide, tooth remineralization
  • İstanbul Medipol Üniversitesi Adresli: Evet

Özet

Background: This study aimed to investigate the efficacy of three remineralizing agents on dental erosion in primary teeth. Methods: Forty primary molars were randomly divided into four groups (n = 10 each): self-assembling peptide (P11–4), casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP), sodium fluoride (NaF) and artificial saliva (AS; control). The erosion-like formation was created by immersing the samples in citric acid (4 × 2 min, pH 2.3) and AS (4 × 2 h, pH 7). The eroded samples were then treated with remineralizing agents and subjected to further erosion consisting of 15 cycles (3x/8-h interval) of immersion in citric acid and AS for 6 s each. Alterations in the mineral content and morphology of the samples were quantified using a microhardness tester and atomic force microscope. Results: All agents had a significant remineralization effect on eroded primary tooth enamel. After further erosive challenge, enamel loss in the CPP-ACFP group was found to be significantly lower than in all other groups, and no significant difference was found between the P11–4 and NaF groups. Conclusions: This study showed that all tested materials had remineralization ability, and CPP-ACFP had a superior effect in inhibiting enamel loss due to dental erosion in primary teeth. © 2022 Australian Dental Association.