Unilateral segmental fixed drug eruption induced by sertraline: case report

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Balev A., Üstüner P. D., Özdemr M., Erdoǧanb A. Ç.

Turkiye Klinikleri Dermatoloji, vol.27, no.2, pp.72-74, 2017 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.5336/dermato.2016-51179
  • Journal Name: Turkiye Klinikleri Dermatoloji
  • Journal Indexes: Scopus
  • Page Numbers: pp.72-74
  • Keywords: Drug eruptions, Herpes zoster, Sertraline
  • Istanbul Medipol University Affiliated: Yes


Fixed drug eruption (FDE) is a common dermatological disease, and its etiological mechanism is currently uncertain. FDE may occurs in both sexes and in all age groups. It develops after intake of a responsible drug and always occurs at the same sites. FDE usually appears as a solitary or a small number of pruritic, well circumscribed, erythematous macules that evolve into edematous plaques. Sertraline is a selective serotonin reuptake inhibitor and commonly used drug for depression. Some dermatologic side effects such as rash, pruritus, dermatitis, purpura, urticaria, and Steven-Johnson syndrome were reported in the literature. We present a case of segmental FDE following use of sertraline for depression in a 25-year-old man. Given the wide use of this substance in psychiatry , clinicians should be aware of this potential complication.