Efficacy of adjunctive mitomycin C in transcanalicular diode laser dacryocystorhinostomy

ÖZSÜTÇÜ M., Balci O., TANRIVERDİ C., DEMİRCİ G.

European Archives of Oto-Rhino-Laryngology, vol.274, no.2, pp.873-877, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 274 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.1007/s00405-016-4308-7
  • Journal Name: European Archives of Oto-Rhino-Laryngology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.873-877
  • Keywords: Nasolacrimal duct obstruction, Mitomycin C, Transcanalicular laser dacryocystorhinostomy
  • Istanbul Medipol University Affiliated: Yes

Abstract

The objective of the study was to compare the success rate of transcanalicular laser dacryocystorhinostomy (TCL-DCR) with or without the use of adjunctive mitomycin C (MMC) in cases with primary nasolacrimal duct obstruction (NLDO). This retrospective study was comprised of 68 patients with uncomplicated primary NLDO. There were two groups in the study: the Group 1 (n = 35) patients underwent TCL-DCR surgery with MMC and the Group 2 (n = 33) patients underwent TCL-DCR surgery without MMC. All patients had bicanalicular silicone tube intubation. The main outcome measures were patent osteotomy as visualized endoscopically and patent nasolacrimal irrigation. The follow-up period was 12 months. All patients had unilateral TCL-DCR with silicone tube intubation. Six months following surgery, the silicone tubes were removed. At the final evaluation, success rates were 80 % in Group 1 and 78.8 % in Group 2. There was no statistically significant difference between the two groups (p = 0.52). No complications related to MMC usage were recorded during the study period. Intraoperative use of MMC has no beneficial effect on the success rate in TCL-DCR.