Efficacy of adjunctive mitomycin C in transcanalicular diode laser dacryocystorhinostomy

ÖZSÜTÇÜ M., Balci O., TANRIVERDİ C., DEMİRCİ G.

European Archives of Oto-Rhino-Laryngology, cilt.274, sa.2, ss.873-877, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 274 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s00405-016-4308-7
  • Dergi Adı: European Archives of Oto-Rhino-Laryngology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.873-877
  • Anahtar Kelimeler: Nasolacrimal duct obstruction, Mitomycin C, Transcanalicular laser dacryocystorhinostomy
  • İstanbul Medipol Üniversitesi Adresli: Evet

Özet

The objective of the study was to compare the success rate of transcanalicular laser dacryocystorhinostomy (TCL-DCR) with or without the use of adjunctive mitomycin C (MMC) in cases with primary nasolacrimal duct obstruction (NLDO). This retrospective study was comprised of 68 patients with uncomplicated primary NLDO. There were two groups in the study: the Group 1 (n = 35) patients underwent TCL-DCR surgery with MMC and the Group 2 (n = 33) patients underwent TCL-DCR surgery without MMC. All patients had bicanalicular silicone tube intubation. The main outcome measures were patent osteotomy as visualized endoscopically and patent nasolacrimal irrigation. The follow-up period was 12 months. All patients had unilateral TCL-DCR with silicone tube intubation. Six months following surgery, the silicone tubes were removed. At the final evaluation, success rates were 80 % in Group 1 and 78.8 % in Group 2. There was no statistically significant difference between the two groups (p = 0.52). No complications related to MMC usage were recorded during the study period. Intraoperative use of MMC has no beneficial effect on the success rate in TCL-DCR.