Standardized uptake values highly correlate with tumor size and Fuhrman grade in patients with clear cell renal cell carcinoma

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Polat E. C., Otunctemur A., Ozbek E., Besiroglu H., Dursun M., Ozer K., ...More

Asian Pacific Journal of Cancer Prevention, vol.15, no.18, pp.7821-7824, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 18
  • Publication Date: 2014
  • Doi Number: 10.7314/apjcp.2014.15.18.7821
  • Journal Name: Asian Pacific Journal of Cancer Prevention
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.7821-7824
  • Keywords: F-18 FDG PET/CT, SUVmax, renal carcinoma, Fuhrman grade, tumor size
  • Istanbul Medipol University Affiliated: Yes

Abstract

Background: We investigated the correlation between standardized uptake value (SUVmax), tumor size and Fuhrman grade in patients with renal cell carcinoma (RC). Materials and Methods: We retrospectively analyzed the data of 54 patients with clear cell renal cell carcinoma histopathologically diagnosed who underwent fluorine-18 fluoro-2 deoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) between January 2005 and March 2014. Results: Avarage tumor sizes were 5.64±1.85, 6.85±2.24 and 7.98±2.45 in low, medium and high SUVmax groups, respectively. The Spearman's correlation coefficient between the tumor size and SUVmax was 0.385 (p=0.004) and between the Fuhrman grade and SUVmax was 0.578 (p<0.001). Conclusions: SUVmax appears highly correlated with tumor size and Fuhrman grade in patients with histopathologically confirmed clear cell RC. Multicenter studies are needed to provide larger series for more accurate results.