Bone Scintigraphy in Cleidocranial Dysplasia

YILDIRIM M., Ersoz M., ALPER F., Seven B., Uslu H., Tozoglu S., ...More

Clinical Nuclear Medicine, vol.29, no.1, pp.65-67, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 1
  • Publication Date: 2004
  • Doi Number: 10.1097/01.rlu.0000102745.70984.df
  • Journal Name: Clinical Nuclear Medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.65-67
  • Keywords: cleidocranial dysplasia, bone scintigraphy, clavicular defect
  • Istanbul Medipol University Affiliated: No

Abstract

Cleidocranial dysplasia (CLCD) is an autosomal-dominant disorder. There is altered bone formation with clavicular hypoplasia or agenesis with a narrow thorax, causing approximation of the shoulders in front of the chest occurring with delayed ossification of the skull, excessively large fontanelles, and delayed closure of the sutures. More than 100 additional anomalies can be associated, including dental abnormalities, delayed skeletal maturation, hearing deficiency, and mild mental retardation in some cases. Scintigraphic images showed delayed epiphyseal closure, which can be seen in this disease.