Bioautography for evaluation of several Lavandula L. and Origanum species antimicrobial and antioxidant activity


Acta Pharmaceutica Sciencia, vol.61, no.2, pp.141-151, 2023 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 2
  • Publication Date: 2023
  • Doi Number: 10.23893/1307-2080.aps6110
  • Journal Name: Acta Pharmaceutica Sciencia
  • Journal Indexes: Scopus, EMBASE
  • Page Numbers: pp.141-151
  • Keywords: antioxidant, bioautography, essential oil, Lavandula, Origanum
  • Istanbul Medipol University Affiliated: Yes


In the search of bioactive natural compounds, bioautography of plant extracts were associated in an antioxidant screening. Due to containing variety of phenolic compounds Lavandula and Origanum species are important medicinal plants. The antioxidant and free radical scavenging activities of Lavandula angustifolia, L. stoechas, L. heterophylla, Origanum majorana, O. onites, O. vulgare, O. minituflorum, and their main phenolic compounds linalool and carvacrol was carried out by TLC-bioautography method based on the DPPH· andABTS·+ assays to compare essential oils and known main active constituents. The antimicrobial activity of the materials was tested using the in vitro broth microdilution assay towards two different microorganisms. Methicillin-resistant Staphylococcus aureus and Streptococcus mutans were used for the study. As a result of our studies, it is determined that O. vulgare showed the highest activity against S. mutans and O. onites and O. vulgare showed the highest activity against MRSA. compared to the tested antibiotic.