Efficacy of periarticular injection applied trough knee other than posterior capsule in simultaneous bilateral total knee arthroplasty

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Guler O., Mutlu S., Isyar M., Mutlu H., Bulbul A. M., Mahirogullari M.

Journal of Orthopaedics, vol.12, no.4, pp.205-210, 2015 (Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.1016/j.jor.2015.05.012
  • Journal Name: Journal of Orthopaedics
  • Journal Indexes: Scopus
  • Page Numbers: pp.205-210
  • Keywords: Periarticular drug injection, Total knee arthroplasty, Range of motion, Visual analog scale scores, Postoperative pain management
  • Istanbul Medipol University Affiliated: Yes


Background: We aimed to evaluate periarticular multimodal drug injection (PMDI) in bilateral total knee arthroplasty. Methods: In 154 knees of 77 patients, PMDI was administered intraoperatively through the regions other than posterior capsule to one knee; other knee was control. Results: Drug-injected knees had lower visual analog scale scores and higher passive range of motion postoperatively (p < 0.05). The active straight leg raise was higher in drug-injected knees (47 [61%] vs 19 [24.7%], p = 0.001). Conclusions: PMDI is a safe and effective method of early postoperative pain management in total knee arthroplasty when applied through regions other than posterior capsule.