18F-FDG-PET correlates of impulse control disorder in a diabetic patient
Endocrine, Metabolic and Immune Disorders - Drug Targets, cilt.16, sa.3, ss.224-227, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 16 Sayı: 3
- Basım Tarihi: 2016
- Doi Numarası: 10.2174/1872214810666160930124951
- Dergi Adı: Endocrine, Metabolic and Immune Disorders - Drug Targets
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.224-227
- Anahtar Kelimeler: Diabetes mellitus, FDG-PET, impulse control disorder
- İstanbul Medipol Üniversitesi Adresli: Evet
Özet
Background: Studies have already shown that hyperglycemia and insulin resistance are significantly associated with the impairment of cerebral glucose metabolism that may secondary lead to cognitive disturbances. In this study, we aimed to evaluate the neurometabolic correlates of diabetes in a patient with Intermittent explosive disorder (IED). Methods: We have investigated the cerebral glucose metabolism via 2-[18F]-fluoro-2- deoxy-D-glucose positron emission tomography (FDG-PET) in a diabetic patient with aggressive outbursts. Results: We have found significantly reduced glucose uptake in left temporoparietal region, pontin area, and left nucleus lentiformis. Discussion: Our present results indicate decreased cerebral glucose metabolism in specific cerebral cortical and subcortical areas. The main limitation of this report is that, this is a single case study and that these findings need to be replicated in well- conducted randomized controlled studies by using additional neuroquantitative methods.