Ceasing Vitamin D Replacement in Infants with Premature Closure of Front Fontanelle: True or False?


Meandros Medical And Dental Journal, vol.21, no.3, pp.244-250, 2020 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 3
  • Publication Date: 2020
  • Journal Name: Meandros Medical And Dental Journal
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.244-250
  • Keywords: Vitamin D, anterior fontanelle closure, child
  • Istanbul Medipol University Affiliated: No


Objective: The purpose of this study was to determine whether fontanelle closurein neonatal and early infantry periods was related to vitamin D levels and theprophylaxis of vitamin D intake. Moreover, our analysis was structured in aretrospective, controlled manner to evaluate our hypothesis.Materials and Methods: We considered 50 individuals who applied to our childendocrinology polyclinic with infants suffering from premature anterior closure.Further, 35 healthy infants of the same age and gender having open anteriorfontanelles were taken as the control group.Results: The serum vitamin D level was found to be lower, and the parathormonelevel was significantly higher in the group with premature closure of the anteriorfontanelle. In addition, there was a significant difference in serum calcium, alkalinephosphatase and parathormone levels in patients who had ceased vitamin D support compared with regular vitamin D users. While there was no significant difference in serum vitamin D levels, the level was lower in patients who had withdrawn vitamin D support.Conclusion: In our study, many infants have much lower vitamin D levels thannormal levels, even though their anterior fontanelle is prematurely closed. Thus,physicians and other health workers are also warned of the continuity of vitamin Dprophylaxis and that it is wrong to cease vitamin D support for reasons such as thepremature closing of the anterior fontanelle.