Value of Renal Vascular Doppler Sonography in Cardiorenal Syndrome Type 1

Çakal B., ÖZCAN Ö. U., Omaygenç M. O., KARACA I. O., Kızılırmak F., GÜNEŞ H. M., ...More

Journal of Ultrasound in Medicine, vol.40, no.2, pp.321-330, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.1002/jum.15404
  • Journal Name: Journal of Ultrasound in Medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, CAB Abstracts, CINAHL, Compendex, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.321-330
  • Keywords: decompensated heart failure, diuretics, renal resistive index, venous impedance index
  • Istanbul Medipol University Affiliated: Yes


Objectives: Worsening of renal function in a patient with acute decompensated heart failure is called cardiorenal syndrome (CRS) type 1. Recent studies have shown an association of persistent systemic venous congestion with renal dysfunction. This trial was set up to investigate the changes of renal Doppler parameters with diuretic therapy in patients with CRS type 1. Methods: Cases of CRS type 1 were identified among patients hospitalized for decompensated heart failure. Serial measurements of the renal venous impedance index (VII) and arterial resistive index (ARI) were calculated by pulsed wave Doppler sonography. Results: A total of 30 patients who had creatinine improvement with diuresis (group 1) and 34 patients without any improvement (group 2) were analyzed. Patients in group 1 had higher median VII and ARI (VII, 0.86 versus 0.66; P <.001; ARI, 0.78 versus 0.65; P <.001) on admission. A high ARI on admission (odds ratio, 6.25; 95% confidence interval, 1.84–14.3; P =.003) predicted the improvement of serum creatinine levels with diuretic therapy independent of confounding factors in patients with CRS type 1. Conclusions: Renal vascular Doppler parameters might offer guidance on the diagnostic and therapeutic strategies in prescribing decongestive therapy for decompensated heart failure.