The efficacy of fluoxetine in the treatment of premature ejaculation: A double-blind placebo controlled study

Kara H., Aydin S., Aǧargün M. Y., Odabaş Ö., Yilmaz Y.

Journal of Urology, cilt.156, sa.5, ss.1631-1632, 1996 (Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 156 Sayı: 5
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1016/s0022-5347(01)65467-3
  • Dergi Adı: Journal of Urology
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.1631-1632
  • Anahtar Kelimeler: fluoxetine, ejaculation, psychosexual dysfunctions
  • İstanbul Medipol Üniversitesi Adresli: Hayır

Özet

Purpose: The efficacy of the selective serotonin re-uptake inhibitor fluoxetine in the treatment of premature ejaculation was examined. Materials and Methods: The study comprised 17 patients with premature ejaculation who presented to the urology clinic of our medical school. In this double-blind study the patients were randomized into treatment groups receiving 20 mg. fluoxetine daily for 1 week and 40 mg. daily afterward (group 1) or 1 capsule placebo daily for i week and 2 capsules daily afterward (group 2). The groups were evaluated according to the latent period of intravaginal ejaculation. Results: The latent period of intravaginal ejaculation in group 1 was significantly longer than that in group 2. Nausea, headache and insomnia were reported side effects. Conclusions: Fluoxetine may be regarded as a safe and effective alternative in the treatment of premature ejaculation.