Effect of intracanal medicaments used in endodontic regeneration on the push-out bond strength of a calciumphosphate-silicate-based cement to dentin

Oktay E. A., Ersahan Ş., GÖKYAY S. S.

Pakistan Journal of Medical Sciences, vol.34, no.2, pp.310-315, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.12669/pjms.342.14630
  • Journal Name: Pakistan Journal of Medical Sciences
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.310-315
  • Keywords: Bond strength, Endosequence Root Repair Material (ERRM), Intracanal medicaments, Push-out test, Regenerative endodontic treatment
  • Istanbul Medipol University Affiliated: Yes


Objective: To evaluate the effects of various endodontic regeneration agents on the push-out bond strength of Endosequence Root Repair Material (ERRM) to root-canal dentin. Methods: Fifty single-rooted human teeth were selected and instrumented to obtain a standard internal diameter of 1.5 mm. Specimens were randomly divided into four experimental groups and treated with an intracanal medicament [calcium hydroxide (CH), double antibiotic paste (DAP), triple antibiotic paste (TAP), TAP with amoxicillin (mTAP)] and a non-treated control group. Medicaments were removed after three weeks, and ERRM was applied to all specimens. The coronal portion of each root was then sliced into 2-mm-thick parallel transverse sections (2 slices per tooth, n=20 slices per group), and a push-out test was used to measure the bond strength of ERRM to dentin. Data were analyzed using Bonferroni-corrected Mann-Whitney tests, with the level of significance set at p<0.05. Results: The push-out bond strength of the CH group was significantly higher than that of the TAP, DAP and mTAP groups (p< 0.005). Furthermore, the bond strength of the control group was higher than the bond strength of both the DAP and mTAP groups. Conclusion: The use of CH in clinical practice may help improve the adhesion of ERRM to dentin.