Tear osmolarity and ocular surface parameters in patients with psoriasis Parâmetros de osmolaridade lacrimal e da superficie ocular em pacientes com psoríase

DEMİRCİ G., Erdur S. K., Aydin R., BALEVİ A., ELİAÇIK M., ÖZSÜTÇÜ M., ...More

Arquivos Brasileiros de Oftalmologia, vol.80, no.1, pp.1-3, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 80 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.5935/0004-2749.20170002
  • Journal Name: Arquivos Brasileiros de Oftalmologia
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1-3
  • Keywords: Dry eye syndromes, Tears, Osmolar, Psoriasis, Tear film
  • Istanbul Medipol University Affiliated: Yes


Purpose: The aim of this study was to evaluate tear osmolarity, tear film function, and ocular surface changes in patients with psoriasis. Methods: At a single center, 30 eyes of 30 patients with psoriasis (group 1) and 30 eyes of 30 healthy individuals (group 2) were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear film break-up time (TBUT) test, scoring of ocular surface fluorescein staining using a modified Oxford scale, and tear osmolarity measurement. Results: Tear osmolarity values, OSDI, and Oxford scale scores were significantly higher in group 1 (309.8 ± 9.4 mOsm, 38.9 ± 1.1, and 0.7 ± 1.1, respectively) than in group 2 (292.7 ± 7.7 mOsm, 4.2 ± 0.3, and 0.1 ± 0.3, respectively; p<0.01 for all). TBUT was significantly lower in group 1 (8.7 ± 3.6 s) than in group 2 (18.1 ± 2.8 s; p<0.001). No significant differences were detected in Schirmer I test values between the groups (16.2 ± 2.5 mm in group 1 and 16.6 ± 2.3 mm in group 2; p=0.629). Conclusions: The results of this study showed that psoriasis may influence tear osmolarity and tear film function. Patients with psoriasis showed tear hyperos-molarity and tear film dysfunction.