RIFAMPICIN: An antibiotic with brain protective function

Yulug B., HANOĞLU L., Kilic E., Schabitz W. R.

Brain Research Bulletin, vol.107, pp.37-42, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 107
  • Publication Date: 2014
  • Doi Number: 10.1016/j.brainresbull.2014.05.007
  • Journal Name: Brain Research Bulletin
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.37-42
  • Keywords: Rifampicin, Stroke, Parkinson's disease, Alzheimer's disease, Optic nerve injury, Meningitis
  • Istanbul Medipol University Affiliated: Yes


Besides its well known antibiotic activity rifampicin exerts multiple brain protective functions in acute cerebral ischemia and chronic neurodegeneration. The present mini-review gives an update of the unique activity of rifampicin in different diseases including Parkinson's disease, meningitis, stroke, Alzheimer's disease and optic nerve injury. © 2014 Elsevier Inc.