The evaluation of aortic elasticity in subclinical hypothyroidism Subklinik hipotiroidide aort elastisitesinin değerlendirilmesi

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Özkan S., DUMAN D., Tarim M. A., Demirtunç R.

Marmara Medical Journal, vol.28, no.3, pp.135-141, 2015 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.5472/mmjoa.2803.03
  • Journal Name: Marmara Medical Journal
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.135-141
  • Keywords: Aortic stiffness, Subclinical hypothyroidism, Left ventricular diastolic dysfunction
  • Istanbul Medipol University Affiliated: Yes


Objective: In this study we evaluated the elastic properties of the aorta in patients with subclinical hypothyroidism and their relation with left ventricular diastolic function by transthoracic echocardiography. Patients and Methods: Aortic transthoracic echocardiography was performed and the aortic elasticity was evaluated using the following parameters; strain, the beta index and distensibility. Results: There was significant difference in terms of aortic strain (5.79% vs. 9.45% p <0.001) and distensibility (4.64 versus 3.02 10-3.cm2. dyn-1. p <0.005) between the control group and patients with subclinical hypothyroidism group. In the subclinical hypothyroidism group the average mitral early diastolic velocity (E). (p <0.05) were significantly lower than the mean mitral diastolic flow velocity/mitral late diastolic flow velocity (E/A) (p <0.01) observed in the control group. and higher than the mean mitral late diastolic flow velocity (A) and isovolumetric relaxation time (IVRT) (P <0.05) in the control group. Conclusions: In patients with subclinical hypothyroidism an increase in the aortic stiffness was observed. The diastolic dysfunction observed in subclinical hypothyroidism is mainly responsible for the increase in the aortic stiffness.