Retrospective Evaluation of Covid-19 Patients Treated with Extracorporeal Membrane Oxygenation and Cannulation Types Applied


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KAMİLÇELEBİ N., YILDIZ Y.

Comprehensive medicine, cilt.15, sa.1, ss.6-10, 2023 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.14744/cm.2022.85579
  • Dergi Adı: Comprehensive medicine
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.6-10
  • İstanbul Medipol Üniversitesi Adresli: Evet

Özet

Objective: Pneumonia associated with the novel coronavirus disease 2019 (COVID-19) can lead to respiratory failure with deep hypoxemia requiring endotracheal intubation and mechanical ventilation. Patients who do not respond to optimal conventional mechanical ventilation may be candidates for administration by extracorporeal membrane oxygenation (ECMO) in institutions with appropriate resources (equipment and personnel). This study aimed to compare the effects of cannulation types on mortality. Materials and Methods: Patients followed up at the intensive care unit between April 2020 and May 2021 with the diagnosis of COVID-19 and who received ECMO support were screened. Demographic data of the patients, initiation of ECMO, ECMO type, type of inserted cannula, duration of intubation, intensive care unit and hospital stays, P/F levels were collected from the Hospital Information Management System and retrospectively analyzed. Results: Among the patients with ARDS who underwent ECMO, 4 were females and 24 were males. When hemodynamic parameters were compared, no statistically significant difference was found between the groups. All patients needed high doses of inotropic agents. Of the 28 Covid-19 patients who underwent ECMO, 25 (89.3%) died. Eight patients left ECMO, but only 3 of the patients who left ECMO were discharged. No statistically significant difference was found in terms of the onset of ECMO after intubation (p=0.62). Mean ECMO time applied to the patients was determined as 10.6±9.6 days. Conclusion: ECMO is a rescue treatment requiring the participation of a multidisciplinary team of experienced medical professionals with training and expertise in initiating, maintaining and discontinuing ECMO in critical patients.