Intense fluoro-2-deoxyglucose uptake in high-grade prostatic adenocarcinoma with negligible prostate-specific membrane antigen expression

ÇAKIR T., Guven S., MÜEZZİNOĞLU B., EROL C., Boz M., ATASEVER T.

Urology Annals, vol.11, no.4, pp.439-442, 2019 (Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.4103/ua.ua_11_19
  • Journal Name: Urology Annals
  • Journal Indexes: Scopus
  • Page Numbers: pp.439-442
  • Keywords: F-18-labeled fluoro-2-deoxyglucose positron emission tomography, computed tomography, (68)gallium prostate-specific membrane antigen positron emission tomography, computed tomography, multiparametric magnetic resonance imaging, prostate cancer
  • Istanbul Medipol University Affiliated: Yes

Abstract

While 68Gallium prostate-specific membrane antigen positron emission tomography/computed tomography (68Ga-PSMA) has demonstrated increasing utility in the evaluation of prostatic carcinoma, it is essential to be aware of false-negative findings. Further subtype analyses of prostate cancer will be helpful in the understanding of the underlying reasons. We herein present a high-grade prostate adenocarcinoma, with metastatic lesions showing high 18F-labeled fluoro-2-deoxyglucose uptake instead of 68Ga-PSMA.