The comparison of physical activity status, exercise perception and quality of life between clinically isolated syndrome and multiple sclerosis patients Klinik izole sendrom ve multipl skleroz hastalarinda fiziksel aktivite düzeyi, egzersiz algisi ve yaşam kalitesinin karşilaş tinlmasi

Ertekin Ö., ÖZAKBAŞ S., Çinar B. P., ALGUN Z. C., Idiman E.

Noropsikiyatri Arsivi, vol.50, no.2, pp.116-121, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.4274/npa.y6214
  • Journal Name: Noropsikiyatri Arsivi
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.116-121
  • Keywords: Clinically isolated syndrome, multiple sclerosis, physical activity, quality of life
  • Istanbul Medipol University Affiliated: Yes


Background: To determine and to compare the activity status, quality of life, exercise perception and fatigue in patients with clinically isolated syndrome (CIS) and multiple sclerosis (MS), both in remission. Method: Demographic and medical statuses of 12 CIS and 9 MS patients, who were included in the study, were recorded. Disability [The Expanded Disability Status Scale (EDSS)], pain [Visual Analog Scale (VAS)], walking difficulties [The 12-ltem Multiple Sclerosis Walking Scale (MSWS-12)] fatigue [The Fatigue Impact Scale (FIS)], quality of life [The MS International Quality of Life questionnaire (MUSIQoL)], results of symptoms/limitations [The MS Impact Scale (MSIS-29)], exercise participation [The Exercise Benefits and Barriers Scale (EBBS)] and physical activity status [The Physical Activity and Disability Survey (PADS), - with one question)] were evaluated. Results: There was no any significant differences between MS and CIS patients according to EDSS and VAS scores (p=0.503, p=0.066, respectively). The differences in mean scores of MSWS-12(p=0.405|, MSIS-29(p=0.226), MUSIQoL(p=0.117), FIS-tot(p=0.302), FIS-cog (p=0.801), FlS-phy (p=0.298), FIS-soc (p=0.163) and PADS (p=0.085) between the groups were not statistically significant Additionally, all subjects reported activity avoidance and lower activity status after the diagnoses. The differences in mean scores of EBBS-total, EBBS-benefit and the EBBS-barrier between the groups were not statistically significant (p=0 374, p=0.569, p=0.255, respectively). A significant positive correlation was found between the MUSIQoL and FIS-total (p=0.039); MUSIQoL and MSIS-29 (p=0.001); MSWS-12 and MSIS-29 (p=0.010). Conclusion: It was found that the patients with newly diagnosed CIS and MS.both in remission have diminished their activity status and exercise participation in the same way. Besides, they developed activity avoidance with negatively influenced quality of life and fatigue. The possible and rapid alterations in physical activity level in these patients may be useful for rehabilitation teams to develop new strategies for reducing these negative effects. © Archives of Neuropsychiatry.