Epstein-barr virus-associated haemophagocytic lymphohistiocytosis presenting with acute sensorineural hearing loss: A case report and review of the literature

Arslan F., Karagöz E., BEKÖZ H. S., CEYLAN B., MERT A.

Infezioni in Medicina, cilt.25, sa.3, ss.277-280, 2017 (Scopus) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 25 Sayı: 3
  • Basım Tarihi: 2017
  • Dergi Adı: Infezioni in Medicina
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.277-280
  • Anahtar Kelimeler: Epstein Barr virus, Haemophagocytic lymphohistiocytosis, Hearing loss, Steroid
  • İstanbul Medipol Üniversitesi Adresli: Evet

Özet

Epstein-Barr virus-associated haemophagocytic lymphohistiocytosis (EBV-HLH) is a life-threatening catastrophic and rarely seen complication of EBV infection especially in adults. While typical presentation of EBV infection is easily diagnosed as mononucleosis syndrome in teenagers and adults, some atypical clinical presentations may be challenged. We did not encounter any patient presenting with sudden sensorineural hearing loss associated with EBV infection in our English medical literature research (1966-2016). In this study, we report an adult patient who was complicated with EBV-HLH under high dose steroid therapy after diagnosis as sensorineural hearing loss. Our aim is to emphasise the atypical presentation of EBV infection and to discuss steroid therapy complication in sensorineural hearing loss that had been simply defined as idiopathic.