Anaphylactoid Reactions Following Red Blood Cell Transfusion in a Patient with Previously Undiagnosed Immunoglobulin A Deficiency: Case Report

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GÜNGÖR H., Yanaral T. U., Uzunoğlu E., KARAASLAN P.

Turkish Journal of Anaesthesiology and Reanimation, vol.51, no.2, pp.143-146, 2023 (Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 2
  • Publication Date: 2023
  • Doi Number: 10.5152/tjar.2023.22133
  • Journal Name: Turkish Journal of Anaesthesiology and Reanimation
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.143-146
  • Keywords: Anaphylaxis, blood products, immunoglobulin A, perioperative care, transfusion
  • Istanbul Medipol University Affiliated: Yes


A 73-year-old, 104 kg female patient was hospitalised for debulking and low anterior colon resection operations. Anaphylactoid symptoms devel-oped when administering erythrocyte suspension and fresh frozen plasma. Through the immediate haematology department consultation, it was found that the patient might possibly have immunoglobulin A deficiency. Immunoglobulin A level was found to be very low in the patient’s blood sample, which was sent intraoperatively to verify the diagnosis. This case report discusses a sudden anaphylactic reaction that occurred as a result of a blood transfusion in a previously undiagnosed immunoglobulin A deficiency.