Antimicrobial activity of some centaurium hill taxa growing in Turkey Türkiye'de yetisen bazi centaurium hill taksonlarinin antimikrobiyal aktivites

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Yilmaz G., SImsek D., EksI G., ALTANLAR N., ÇIçek M., YAPRAK A. E.

Ankara Universitesi Eczacilik Fakultesi Dergisi, vol.44, no.3, pp.415-423, 2020 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.33483/jfpau.756312
  • Journal Name: Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Journal Indexes: Scopus, EMBASE
  • Page Numbers: pp.415-423
  • Keywords: Antimicrobial activity, C. erythraea subsp. turcicum, C. maritimum, C. spicatum c. tenuiflorum subsp. acutiflorum, Centaurium erythraea subsp. rhodense
  • Istanbul Medipol University Affiliated: No


Objective: In this study, in vitro antimicrobial activity of ethyl acetate and methanol extracts of the aerial parts of five Centaurium species (Centaurium erythraea subsp. rhodense, C. erythraea subsp. turcicum, C. maritimum, C. spicatum, and C. tenuiflorum subsp. acutiflorum), which are naturally grown in Turkey were intended to be tested against selected Gram positive and Gram negative bacteria; and a yeast Candida albicans by using broth microdilution method. Material and Method: Methanol and ethyl acetate extracts of aerial parts were obtained from each of the Centaurium plants collected from Ege (Mugla, Denizli, Izmir) and Akdeniz (Antalya) Regions in Turkey tested on S. aureus ATCC 29213, E. faecalis ATCC 29212, E. coli ATCC 25922, K. pneumoniae ATCC 13883, P. aeruginosa ATCC 27853 as bacteria and C. albicans ATCC10231 as yeast by using broth microdilution method. Result and Discussion: The methanol extracts of all Centaurium species have indicated moderate antimicrobial activities against S. aureus, E. faecalis, E. coli, K. pneumoniae, P. aeruginosa and C. albicans, but ethyl acetate extract have no activity.