Habituation of the auditory evoked potential in a short interstimulus interval paradigm

Ozesmi C., Dolu N., SÜER C., Golgeli A., Ascioglu M.

International Journal of Neuroscience, cilt.105, sa.1-4, ss.87-95, 2000 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 105 Sayı: 1-4
  • Basım Tarihi: 2000
  • Doi Numarası: 10.3109/00207450009003268
  • Dergi Adı: International Journal of Neuroscience
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.87-95
  • Anahtar Kelimeler: Event related potentials, Habituation, Short interstimulus interval
  • İstanbul Medipol Üniversitesi Adresli: Hayır

Özet

The present experiment was carried out to investigate elicitation and habituation of the auditory event related potentials with stimulus trains utilizing a short interstimulus intervals (ISI) of 1500 ms. Scalp event related potentials elicited by auditory stimuli were recorded in 10 male subjects. Thirty auditory stimuli were presented binaurally over headphones to every subject with a duration of 1000ms, each with a constant ISI of 1500 ms. No task relevance was given to the stimuli. Wave-forms were collected using a Pentium 100 computer. All analyses were carried out over the 30 trials. In each single trial event related potentials, latencies and amplitudes of N1-P2 components were analyzed separately for four frequency bands (0.3-70, 0.3-4, 4-7, 7-13 Hz). Trend effects were tested with linear-regression analyses (N1-P2 amplitude x stimuli number). We found that the amplitude from the first stimulus decreased reliably across trial blocks of the N1 - P2 components and that it was directly affected by ISI. The relevance of these results for the habituation is discussed.