A brief report: Cerebrospinal fluid rhinorrhea after repetitive nasal swab testing for coronavirus disease 2019(COVID-19)

YILMAZ M., Bahadır Z., Madendere B., Yüksel R. T., Gökay H., Yiğitbaşı A. A.

Otolaryngology Case Reports, vol.20, 2021 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 20
  • Publication Date: 2021
  • Doi Number: 10.1016/j.xocr.2021.100313
  • Journal Name: Otolaryngology Case Reports
  • Journal Indexes: Scopus
  • Keywords: Cerebrospinal Fluid Rhinorrhea, COVID-19, nasal swab test, Rhinorrhea, RT-PCR, SARS-COV-2
  • Istanbul Medipol University Affiliated: Yes


For the past year, COVID-19 Pandemic has been the biggest focal point of medicine. Due to its novelty and its highly infectious nature, the impact of Sars-Cov-2 on society has been growing rapidly. The primary route for prevention of this highly infectious virus is detection. The detection methods for Sars-Cov-2 include nasal swab tests, saliva samplings and antibody tests. The main preferred method has been the RT-PCR with Nasal Swab sampling which is performed on the nasopharyngeal region. However, the nasal swab testing may come with its own iatrogenic outcomes due to its invasiveness. In this report, we describe a rare case of iatrogenic unilateral cerebrospinal fluid rhinorrhea which occurred due to repetitive nasal swab testing for COVID-19.