Effects of regular moderate exercise on arterial stiffness and PTX3 protein and some cardiac parameters

Karakus M., Dolu N., Saka T., KALAY N., AKKURT S., ÇETİN A., ...More

Studies on Ethno-Medicine, vol.10, no.3, pp.288-294, 2016 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1080/09735070.2016.11905499
  • Journal Name: Studies on Ethno-Medicine
  • Journal Indexes: Scopus
  • Page Numbers: pp.288-294
  • Keywords: Exercise, Pentraxin 3, Pulse wave velocity, Stiffness
  • Istanbul Medipol University Affiliated: No


This study intends to show some of the effects of long-term and regular moderate exercise on arterial stiffness, Pentraxin 3 (PTX3) levels and some cardiac parameters in individuals of middle and advanced age. Twenty mountaineers and twenty sedentary individuals were subjects of this study. Each mountaineer and the individuals in the control group were measured for lipid profile, complete blood count, and underwent echocardiography, and exercise stress test. Central and peripheral pulse wave velocity was measured. The plasma Pentraxin 3 protein was assayed. Metabolic equivalent and PTX3 levels were found to be significantly higher in mountaineers, compared to the sedentary group. Femoral-ankle pulse wave velocity, carotid-femoral pulse wave velocity, left ventricular end-systolic diameter and the neutrophil to lymphocyte ratio were found to be significantly lower in mountaineers, compared to the sedentary group (p<0.05). Long-term and regular, moderate exercise significantly decreases indicators of systemic inflammation and arterial stiffness.